This page was produced as part of as undergraduate course at Davidson College.
Isocitrate Dehydrogenase Structure
for NAD and NADP forms
| Structure: | Isocitrate Dehydrogenase Complexed With Isocitrate, Nadp+, and Calcium (Flash-Cooled) |
| Authors: | B. L. Stoddard, A. Mesecar, D. E. Koshland Junior |
| Exp. Method: | X-ray Diffraction |
| Classification: | Oxidoreductase |
| Source: | Escherichia Coli |
| Citation: | Mesecar, A. D., Stoddard, B. L., , D. E. Koshland Jr.: Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences. Science 277 pp. 202 (1997) |
| Structure: | Isocitrate Dehydrogenase: Structure Of An Engineered Nadp+ --> Nad+ Specificity-Reversal Mutant |
| Authors: | J. H. Hurley |
| Exp. Method: | X-ray Diffraction |
| Classification: | Oxidoreductase |
| Source: | Escherichia Coli |
| Primary Citation: | Hurley, J. H., Chen, R., Dean, A. M.:
Determinants of cofactor specificity in isocitrate dehydrogenase:
structure of an engineered NADP+ --> NAD+ specificity-reversal
mutant. Biochemistry 35 pp. 5670 (1996) |
Chime images and information obtained from the Protein Data Bank.
Contact: Peter Leese or view Molecular Biology at Davidson