LOCUS MUSHEXOKB
3071 bp mRNA
ROD 16-JUL-1997
DEFINITION Mus musculus hexokinase (Hk-1) mRNA, complete cds.
ACCESSION L16949
NID g309292
KEYWORDS hexokinase.
SOURCE house mouse.
ORGANISM Mus musculus
Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
Vertebrata; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae;
Murinae; Mus.
REFERENCE 1 (bases 1 to 3071)
AUTHORS Mori,C., Welch,J.E., Fulcher,K.D., O'Brien,D.A.
and Eddy,E.M.
TITLE Unique hexokinase messenger ribonucleic
acids lacking the
porin-binding domain are developmentally expressed in mouse
spermatogenic cells
JOURNAL Biol. Reprod. 49 (2), 191-203 (1993)
MEDLINE 93385326
COMMENT *Reference [1] reports bases 1 through
286; updated sequence to
concur with publication, NCBI: 25-FEB-1997.
FEATURES
Location/Qualifiers
source
1..3071
/organism="Mus musculus"
/strain="CD-1"
/db_xref="taxon:10090"
/clone="Hk1-sb"
/cell_type="germ cell"
/dev_stage="gamete"
/tissue_type="testis"
mRNA
1..3071
/gene="Hk-1"
/evidence=experimental
5'UTR
<1..187
/gene="Hk-1"
gene
1..3071
/gene="Hk-1"
misc_feature 1..117
/gene="Hk-1"
/note="unique region"
/evidence=experimental
misc_feature 118..257
/gene="Hk-1"
/note="region shared with L16948 and L16950"
/evidence=experimental
CDS
188..3025
/gene="Hk-1"
/EC_number="2.7.1.1"
/codon_start=1
/evidence=experimental
/product="hexokinase"
/db_xref="PID:g1850140"
/translation="MGQNCQRGQAVDVEPKIRPPLTEEKIDKYLYAMRLSDEILIDIL
TRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVN
HEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSF
PCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTM
MTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLED
IRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKESLLFEGRITPELLT
RGKFTTSDVAAIETGWELSPDRRWYQAYMRCTQDTHRDKEGVQNAKEILTRLGVEPSH
DDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQY
SRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLSHFRLSK
QALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIPDGTEHGDFLALDLGGTNFR
VLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVSCISDFLDYMGIKGPRMP
LGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLRDAVKRREEFDLDVVAVV
NDTVGTMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEGNQGQMCINMEWGAFG
DNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQ
ISEPLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKR
AAQLCGAGMAAVVQKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCT
VSFLLSEDGSGKGAALITAVGVRLRGDPTNA"
misc_feature 258..1232
/gene="Hk-1"
/note="Hk1 sequence"
/evidence=experimental
misc_feature 1233..1301
/gene="Hk-1"
/note="unique region"
/evidence=experimental
misc_feature 1302..3071
/gene="Hk-1"
/note="Hk1 sequence"
/evidence=experimental
3'UTR
3026..3071
/gene="Hk-1"
/evidence=experimental
BASE COUNT 783 a 789
c 890 g 609 t
ORIGIN
1 ccttaacacc tgggaccatg
gagggccccc ctcttctcaa ggcttgctag gttagaccag
61 taactacatc aaggactcca acccaccagc
tagagaccgt tcctcagaca cctgagaagg
121 atcagaaaac cccgcttctg aggacagaag
acctctggaa aaacagtgta gccatcacct
181 ctacactatg ggacagaact gccagcgagg
acaggctgta gatgttgaac caaaaatacg
241 accccctctc acagaggaaa agattgataa
gtatctgtat gccatgcggc tctctgatga
301 aattctgata gatatcctga cacgcttcaa
gaaagagatg aagaatggcc tctcccggga
361 ttataaccca acggcctccg tcaagatgct
gccaaccttt gtccggtcca ttccggacgg
421 ctcagaaaag ggggatttca ttgcactgga
tctcggcggg tcttcctttc gaatcctgcg
481 ggtgcaggtg aaccacgaga agagtcagaa
cgtcagcatg gagtctgagg tctacgacac
541 cccagagaac atcgtgcacg gcagtggaag
ccagcttttt gatcacgtcg ctgaatgcct
601 cggagacttc atggagaaaa ggaagatcaa
ggacaagaaa ttacccgtgg gattcacgtt
661 ttccttcccg tgccgacaat ccaaaataga
cgaggccgta ctgatcacgt ggacaaagcg
721 gttcaaagcc agtggcgtgg aaggggcgga
tgtggtcaag ctgctgaata aagccattaa
781 gaagcgaggg gactatgacg ctaacattgt
agctgtggtg aatgacacag tggggaccat
841 gatgacctgc ggctacgatg accaacagtg
tgaagtcggc ctgatcattg gcactggcac
901 caatgcttgc tacatggagg aactgcgaca
catcgacctg gtggaaggcg atgaggggag
961 gatgtgtatt aacacggaat ggggagcctt
tggggatgat gggtccctgg aagacattcg
1021 aacagagttt gacagagagt tagaccgggg atccctcaac
cctgggaaac agctgttcga
1081 gaagatggtg agcggcatgt acatggggga gctggtccgg
ctgatcctgg tgaagatggc
1141 caaggaaagc ctcttatttg aagggcgcat tactccagag
ctgctcacga ggggcaagtt
1201 caccactagc gacgtagccg ccattgaaac gggatgggaa
ctctcccctg accgcaggtg
1261 gtaccaggca tatatgaggt gcacacaaga cacccacagg
gataaggaag gcgttcaaaa
1321 tgccaaggaa atcttgaccc gcctgggagt ggagccgtct
cacgatgact gcgtatcggt
1381 ccagcacgta tgcacgatcg tctccttccg atcagccaac
ctggtggctg ccacgctcgg
1441 tgccatcttg aaccgcctgc gggacaataa gggcacgccc
aggctgcgga ccacagttgg
1501 cgtagacggt tctctctaca agatgcaccc acagtattcc
cggcggttcc acaagaccct
1561 gaggcgcctg gtgcctgact cggacgtccg gttcctcctc
tcggagagtg gcagtggcaa
1621 gggagccgcc atggtgaccg ctgtggccta ccgcctggcc
gagcagcacc ggcagattga
1681 ggaaaccctg tcccacttcc gcctcagcaa gcaggcactg
atggaggtga agaagaagct
1741 gcggtcagag atggaaatgg ggctgagaaa ggagaccaac
agcagagcta cggtcaaaat
1801 gctgccttct tatgtgcgga gcatcccaga tgggactgag
catggtgact tcctggcctt
1861 ggatctcgga ggaacgaatt tccgagtcct actggtaaag
atccgtagtg ggaaaaagag
1921 aacagtggag atgcacaaca agatctactc cattcccctg
gaaatcatgc agggcaccgg
1981 ggatgagctg tttgatcaca ttgtctcctg catctccgac
ttcctggact acatggggat
2041 caaaggcccc cggatgcctc tgggcttcac cttctcgttt
ccctgcaagc agacgagcct
2101 agattgcgga atcttgatca cgtggacaaa gggattcaaa
gccaccgact gtgtgggtca
2161 cgatgtagcc actttactga gggatgctgt aaaaaggaga
gaggaatttg acctggatgt
2221 ggtggctgtg gtcaacgaca ccgtgggcac catgatgact
tgtgcttatg aagaaccttc
2281 ttgtgagatt ggactcatcg tggggactgg cagcaatgcc
tgctacatgg aggagatgaa
2341 aaacgtggag atggtggagg ggaaccaggg ccagatgtgc
atcaatatgg aatggggtgc
2401 ctttggtgac aacggctgtc tggacgacat cagaacagac
ttcgacaaag tggtggacga
2461 atattctcta aacagtggga aacaaaggtt tgagaagatg
atcagtggaa tgtacctggg
2521 tgagatcgtc cgtaacatcc tgattgactt caccaagaaa
ggcttcctct tccggggaca
2581 gatctctgag ccactcaaga cccgaggcat cttcgagacc
aagtttctct ctcagatcga
2641 gagtgaccga ttagcgctgc tccaggtgcg ggccatcctt
cagcagctgg gtctaaacag
2701 cacgtgcgac gacagtatcc tggtcaagac cgtgtgtggg
gtggtgtcca agcgggcggc
2761 ccagctgtgt ggtgccggca tggccgccgt ggtgcaaaag
atccgagaga acagaggcct
2821 agaccacctg aatgtaaccg tgggcgtgga cgggacgctc
tacaaactcc atccacactt
2881 ctccagaatc atgcaccaaa cagtgaagga actgtcacca
aagtgtaccg tgtccttcct
2941 cctgtctgaa gacggcagcg gcaagggggc cgcccttatc
acagctgtgg gcgtgcggct
3001 cagaggagac cctacgaacg cctaagagca ggatcctccc
agcccccagc ccgccaccct
3061 tccagcactc c