GenTHREADER PREDICTION RESULTS:
- Key -------------------------------------------------------------
Conf = Description of confidence level
Prob = Estimated probability of correct match
Epair = Pairwise energy for model
Esolv = Solvation energy for model
AlnSc = Sequence alignment score
Alen = Length of alignment
Dlen = Length of PDB entry
Tlen = Length of target sequence
PDB_ID = PDB identifier (+ chain code + domain code in CATH format)
-------------------------------------------------------------------
Confidence levels:
CERT > 99%
HIGH 99%
MEDIUM 90%
LOW 70%
MARG 40%
GUESS < 40%
-------------------------------------------------------------------
Conf Prob Epair Esolv AlnSc Alen DLen
Tlen PDB_ID
=======================================================
LOW 0.616 -79.8 -1.6 42.0
88 97 147 1hs7A0
MARG 0.405 -117.3 8.6 38.0
99 101 147 1d7mA0
MARG 0.378 -70.0 0.6 38.0
83 150 147 1a6jA0
MARG 0.378 -61.1 1.3 37.0
105 128 147 1agrE0
MARG 0.352 -80.4 2.5 33.0
101 107 147 1fxkA0
MARG 0.346 -112.6 4.7 31.0
89 102 147 1qbzA0
MARG 0.313 -55.5 0.3 34.0
92 131 147 1aoa01
MARG 0.308 -66.0 -0.9 37.0
44 44 147 4hb100
GUESS 0.278 -78.3 -1.2 30.0 110
244 147 1ljrA0
GUESS 0.274 -115.3 4.3 30.0
92 284 147 1c1gA0
>>> Alignment with 1hs7A0:
10 20
30
------------------------CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
1hs7A0 ------------------------TNQKTKELSNLIETFAEQSRVLEKECTKIGSKRDSK
| || | | ||
| |
MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSPL---AQRVVTQLSVMSASRKQPK
10 20
30 40
50
40
50 60
70 80
90
HHHHHHHHCHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
1hs7A0 ELRYKIETELIPNCTSVRDKIESNILIHQNGKLSADFKNLKTKYQSLQQSYNQRKSLFPL
|
| || | || | |
| | | | | | |
LLKLARE-DLIKHQT-----IEKCWSIYQQQQRERRNLQLELQYKSIERSMNLLQELSPR
60
70
80 90
100 110
C-----------------------------------
1hs7A0 K-----------------------------------
LFEAANASEKGKRFPMEMKVPTDFPPNTLWHYNFRK
120 130
140
Percentage Identity = 25.8.
>>> Alignment with 1d7mA0:
10
----------------------------------------CHHHHHHHHHHHHHHHHH--
1d7mA0 ----------------------------------------EMANRLAGLENSLESEKV--
| | |
MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSPLAQRVVTQLSVMSASRKQPKLLK
10 20
30 40
50 60
20
30 40
50 60
70
-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1d7mA0 -SREQLIKQKDQLNSLLASLESEGAEREKRLRELEAKLDETLKNLELEKLARMELEARLA
|| |||
|| || | | || | |
|| |
LAREDLIKHQT-IEKCWSIYQQQQRERRNLQLELQYKSIERSMNL-LQELSPRLFEAANA
70 80
90 100
110
80
90 100
HHHHHHHHHHHHHHHHHHHHHHHC-----
1d7mA0 KTEKDRAILELKLAEAIDEKSKLE-----
| | |
SEKGKRFPMEMKVPTDFPPNTLWHYNFRK
130 140
Percentage Identity = 23.8.
>>> Alignment with 1a6jA0:
10 20
30 40
50 60
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEC
1a6jA0 LQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLSLPPQVVFEAILTREKMGSTGIGN
--------------------------------------------------------MLAQ
70 80
90 100
110 120
CEECCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHH
1a6jA0 GIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQPVDLLFALLVPADQTKTHLHTLSLV
|| | |
| | |
TFKKPHRAVLEQVSGTTV-FIRNKRTKSKSSLSPLAQRVVTQLSVMS-ASRKQPKLL---
10 20
30 40
50
130 140
150
HHHHCCHHHHHHHHHCCCHHHHHHHHHCCC------------------------------
1a6jA0 AKRLADKTICRRLRAAQSDEELYQIITDTE------------------------------
| | | | |
------KLAREDLIKHQTIEKCWSIYQQQQRERRNLQLELQYKSIERSMNLLQELSPRLF
60 70
80 90
100 110
----------------------------------
1a6jA0 ----------------------------------
EAANASEKGKRFPMEMKVPTDFPPNTLWHYNFRK
120 130
140
Percentage Identity = 8.2.
>>> Alignment with 1agrE0:
10 20
30 40
50
CCHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHCCCC-HHHHHHHHHHHHHHCCCCCCHHH
1agrE0 VSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSE-ENIDFWISCEEYKKIKSPSKLSP
| | |
| || | |||
-----------------------MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSP
10 20
30
70 80
90 100
110
HHHHHHHHHCCCCCC-CCCCCCHHHHHHHHHHC-CCCCCCCCHHHHHHHHHHHHHCHHHH
1agrE0 KAKKIYNEFISVQAT-KEVNLDSCTREETSRNM-LEPTITCFDEAQKKIFNLMEKDSYRR
|
| | | ||
| | ||
|
LAQRVVTQLSVMSASRKQPKLLKLAREDLIKHQTIEKCWSIYQQQQRERRNLQLELQYKS
40
50 60
70 80
90
120
HCCCHHHHCCC---------------------------------------
1agrE0 FLKSRFYLDLT---------------------------------------
|
|
IERSMNLLQELSPRLFEAANASEKGKRFPMEMKVPTDFPPNTLWHYNFRK
100
110 120
130 140
Percentage Identity = 18.0.
>>> Alignment with 1fxkA0:
10 20
30 40
50
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH----HCCCCCCEEEEECC
1fxkA0 QNVQHQLAQFQQLQQQAQAISVQKQTVEMQINETQKALEELS----RAADDAEVYKSSGN
||| | |
|| | | ||
| | |
-----MLAQTFKKPHRAVLEQVSGTTVFIR-NKRTKSKSSLSPLAQRVVTQLSVMSASRK
10 20
30 40
50
60 70
80 90
100
E--EEEECHHHHHHHH----------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
1fxkA0 I--LIRVAKDELTEEL----------QEKLETLQLREKTIERQEERVMKKLQEMQVNIQE
|
| |
| | |
|| | ||| |
QPKLLKLAREDLIKHQTIEKCWSIYQQQQRERRNLQLELQYKSIERSMNLLQELSPRLFE
60 70
80 90
100 110
CCC------------------------------
1fxkA0 AMK------------------------------
|
AANASEKGKRFPMEMKVPTDFPPNTLWHYNFRK
120
130 140
Percentage Identity = 26.2.
>>> Alignment with 1qbzA0:
10 20
--------------------------------CCHHHHHHHHHHHHHHHHHHHHHHHHHH
1qbzA0 --------------------------------QSRTLLAGIVQQQQQLLDVVKRQQELLR
| || | |
| ||
MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSPLAQRVVTQLSVMSASRKQPKLLK
10 20
30 40
50 60
40 50
60
70
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH---------HHHHHHHHHHHHH
1qbzA0 LTVWGTKNLQTRVTAIEKYLKDQAQLNAWGTPKWNNET---------WQEWERKVDFLEE
|
| | | | |
|| | |
L-------------AREDLIKHQTIEKCWSIYQQQQRERRNLQLELQYKSIERSMNLLQE
70 80
90 100
90 100
HHHHHHHHHHHHHHHHHHHHHHC-----------------
1qbzA0 NITALLEEAQIQQEKNMYELQKL-----------------
| | |
LSPRLFEAANASEKGKRFPMEMKVPTDFPPNTLWHYNFRK
110
120 130
140
Percentage Identity = 20.6.
>>> Alignment with 1aoa01:
10 20
30 40
50
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCC--
1aoa01 YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTI--
|
|
----------------------------------MLAQTFKKPHR--AVLEQVSGTTVFI
10 20
60
70 80
90 100
110
-CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHH
1aoa01 -DERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKI
|
| | | | |||
||| | | |
RNKRTKSKSSLSPLAQRVVTQLSVMSASRKQPKLLKLAREDLI---KHQTIEKCWSIYQQ
30 40
50 60
70 80
120
130
HHHHHHHCCCCCCC----------------------------------------------
1aoa01 GLFADIELSRNEAL----------------------------------------------
|
QQRERRNLQLELQYKSIERSMNLLQELSPRLFEAANASEKGKRFPMEMKVPTDFPPNTLW
90 100
110 120
130 140
------
1aoa01 ------
HYNFRK
Percentage Identity = 13.0.
>>> Alignment with 4hb100:
------------------------------------------------------------
4hb100 ------------------------------------------------------------
MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSPLAQRVVTQLSVMSASRKQPKLLK
10 20
30 40
50 60
10 20
30 40
---CHHHH-HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC------------
4hb100 ---EELLK-QALQQAQQLLQQAQELAKEELLKQALQQAQQLLQQAQEL------------
| | |
| || |
|
|||
LAREDLIKHQTIEKCWSIYQQQQRERRNLQLELQYKSIERSMNLLQELSPRLFEAANASE
70 80
90 100
110 120
---------------------------
4hb100 ---------------------------
KGKRFPMEMKVPTDFPPNTLWHYNFRK
130 140
Percentage Identity = 25.0.
>>> Alignment with 1ljrA0:
10 20
30 40
50 60
CCCEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCEEEEC
1ljrA0 MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDG
------------------------------------------------------------
70 80
90 100
110 120
CEEEECHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHH
1ljrA0 DFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLG
------------------------------------------------------------
130 140
150
160 170
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC------CCCCHHHHHHHHHHH
1ljrA0 PLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAG------QQVTLADLMALEELM
| |
|
-------------MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSPLAQRVVTQLS
10 20
30 40
180 190
200 210
220
H---------HHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHHHHH---C
1ljrA0 Q---------PVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAA---K
| |
|
VMSASRKQPKLLKLAREDLIKHQTIEKCWSIYQQQQRERRNLQL-ELQYKSIERSMNLLQ
50
60 70
80 90
100
230 240
CCCCCCCHHHHHHHHHHHH----CCC---------------
1ljrA0 KTLPTPSPEAYQAMLLRIA----RIP---------------
|
|
|
ELSPRLFEAANASEKGKRFPMEMKVPTDFPPNTLWHYNFRK
110
120 130
140
Percentage Identity = 6.1.
>>> Alignment with 1c1gA0:
10
------------------------------------------------CHHHHHHHHHHH
1c1gA0 ------------------------------------------------MDAIKKKMQMLK
| | | ||
MLAQTFKKPHRAVLEQVSGTTVFIRNKRTKSKSSLSPLAQRVVTQLSVMSASRKQPKLLK
10 20
30 40
50 60
20 30
40 50
60
HHHHHHHHHHHHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1c1gA0 LDKENALDRADEAEA----DKKAAEDRSKQLEDELVSLQKKLKATEDELDKYSEALKDAQ
| |
| | ||| |
||
LAREDLIKHQTIEKCWSIYQQQQRERRNLQLELQYKSIERSMNLLQELSPRLFEAANASE
70 80
90 100
110 120
80 90
100 110
120
HHHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1c1gA0 EKLELAEKKATDAEADVASL---NRRIQLFEEELDRAQERLATALQKLEEAEKAADESER
| | |
KGKRFPMEMKVPTDFPPNTLWHYNFRK---------------------------------
130 140
130
140 150
160 170
180
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
1c1gA0 GMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAEL
------------------------------------------------------------
190
200 210
220 230
240
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1c1gA0 SEGKCAELEEEIKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERS
------------------------------------------------------------
250
260 270
280
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
1c1gA0 VTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
---------------------------------------
Percentage Identity = 12.2.