H. sapiens amino acid sequence used shown in bold.
LOCUS       HSLYSOZY     6807 bp    DNA             PRI       25-JUN-1997
DEFINITION  Human lysozyme gene (EC 3.2.1.17).
ACCESSION   X14008
NID         g34433
KEYWORDS    Alu repetitive sequence; lysozyme; repetitive sequence.
SOURCE      human.
  ORGANISM  Homo sapiens
            Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
            Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae;
            Homo.
REFERENCE   1  (bases 1 to 6807)
  AUTHORS   Sippel,A.E.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-1989) Sippel A.E., ZMBH, Im Neuenheimer Feld 282,
            D-6900 Heidelberg, FRG
REFERENCE   2  (bases 1 to 6807)
  AUTHORS   Peters,C.W., Kruse,U., Pollwein,R., Grzeschik,K.H. and Sippel,A.E.
  TITLE     The human lysozyme gene. Sequence organization and chromosomal
            localization
  JOURNAL   Eur. J. Biochem. 182 (3), 507-516 (1989)
  MEDLINE   89325294
COMMENT     for human lysozyme mRNAs see M19045, J03801 and M21119. Data kindly
            reviewed (21-AUG-1989) by Sippel A. E.
FEATURES             Location/Qualifiers
     source          1..6807
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /clone="lambda HLYS1."
                     /clone_lib="lambda EMBL3"
                     /chromosome="12"
     TATA_signal     491..496
     exon            519..682
                     /number=1
     prim_transcript 519..6374
     mRNA            join(519..682,2246..2410,4349..4427,5281..6374)
     sig_peptide     547..600
     CDS             join(601..682,2246..2410,4349..4427,5281..5347)
                     /EC_number="3.2.1.17"
                     /note="Protein sequence is in conflict with the conceptual
                     translation."
                     /codon_start=1
                     /product="lysozyme"
                     /db_xref="PID:e74526"
                     /db_xref="PID:g1335210"
                     /db_xref="SWISS-PROT:P00695"
                     /translation="KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATN
                     YNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRD
                     PQGIRAWVAWRNRCQNRDVRQYVQGCGV"
     intron          683..2245
                     /number=1
     misc_feature    1120..1440
                     /note="Alu repetitive sequence"
     exon            2246..2410
                     /number=2
     intron          2411..4348
                     /number=2
     misc_feature    2910..3199
                     /note="Alu repetitive sequence"
     exon            4349..4427
                     /number=3
     intron          4428..5280
                     /number=3
     misc_feature    4721..4996
                     /note="Alu repetitive sequence"
     exon            5281..6374
                     /number=4
     misc_feature    5626..5928
                     /note="Alu repetitive sequence"
BASE COUNT     2090 a   1276 c   1204 g   2237 t
ORIGIN      
        1 tctagagtaa gaaactagct gagcaacgtg gtgtcacact atacacccat taagacaaca
       61 ggcacatgtg tcatgtccat tttgtggaaa agatatgtaa aataatttta agtaaaaaag
      121 ataaatataa aaaagtgaat gcatacaaaa caatttcaca aaattgaatg ttactcaaaa
      181 atcacagctc attttaagct gcacaaaata gtcatttttt tctttataat tgctcaaatt
      241 cataatcaaa cagaagaaag ttcctgtctt ggaagtagtg ctatgcccca attcttccag
      301 agccagtact ttaaacaatt ccatttcatt attttcctgt agactaattc ttaggacatc
      361 agcatatctc tcttcaagca ttaaaaaaat ctctttagag tcagtggatc aatagacagt
      421 tcctgttttc cacacaactg aaagggtgga gcccccaaac cacaagggga agaaggaagt
      481 taaaagatgt taaatactgg ggccagctca ccctggtcag cctagcactc tgacctagca
      541 gtcaacatga aggctctcat tgttctgggg cttgtcctcc tttctgttac ggtccagggc
      601 aaggtctttg aaaggtgtga gttggccaga actctgaaaa gattgggaat ggatggctac
      661 aggggaatca gcctagcaaa ctgtaagtct actctccata attccagaga attagctacg
      721 tatggaacag acactaggag agaaggaaga agaagaaggg gctttgagtg aatagatgtt
      781 ttatttcttt gtgggtttgt atacttacaa tggctaaaaa catcagtttg gttctttata
      841 accagagata cccgataaag gaatacgggc atggcagggg aaaattccat tctaagtaaa
      901 acaggacctg ttgtactgtt ctagtgctag gaagtttgct gggtgcctga gattcaatgg
      961 cacatgtaag ctgactgaaa gatacatttg aggacctggc agagctctct caagtccttg
     1021 gtatgtgact ccagttattt cccattttga acttgggctc tgagagccta gagtgatgca
     1081 gtatttttct tgtcttcaag tcccctgccg tgatgtggga tttttatttt tatttttatt
     1141 ttattttatt ttatttttaa agacagtctc actgtgtggc ccaggctgga gtgcagtggc
     1201 atgatctcag ctcactgcaa cctctgcctt ctgggctcaa gtgattctcg tgcttcagcc
     1261 ttctgagtag ctgtgactac aggtgtgtac caccacaccc agctaatttt ttgtattttc
     1321 agtagagatg gggtttcacc atgttggcca agctggtctt gaactcctgg cctcaaatga
     1381 tctgcccacc tcagcctccc aaagtggtag gattacaggt gtgaaccact gcacccagcc
     1441 gacatgggat ttttaacagt gatgttttta aagaatatat tgaattccct acacaagagc
     1501 agtaggaacc tagttccctt cagtcactct ttgtatagga tcccagaaac tcagcatgaa
     1561 atgttttatt atttttatct actctacttg attaactatc tttcattttc tcccacacaa
     1621 ttcaagatgt gccatgagga aaagttattt tatagtttag tacatagttg tcgatgtaat
     1681 aatctctgta gttttcagat tgaattcaga catttcccct caatagctat ttttgaatga
     1741 atgagtgaag ggatgaaatc acggaatagt cttgttttca agattctaac ttgatatcca
     1801 aattcacctt tagatattat aagaaaattt ctatcagaaa atccttatgt ttttctgatt
     1861 aaaaaaagca tttttccatc agcctatgta tctgctatga atttacaaaa tctactcaac
     1921 agctctgttg atttttctgt tcttggctga atgttgcctg agggatggga gcacgggaag
     1981 ggtaaaagca atggaagaaa catgtatttt aatattttaa aagtatgtta tattgttcgt
     2041 tggtgttaca agatgatttg cattacaaaa ggattctctt acaagtccct tatcttaaca
     2101 ctaaagtgct aagatatttt ataagtaaat ctttatactt ataaaacaaa tcagtaaaat
     2161 agaagtagct aagtagaact gattttgcta tagagtataa gtcacttagt gttgctgttt
     2221 attactaaaa ataagttctt ttcagggatg tgtttggcca aatgggagag tggttacaac
     2281 acacgagcta caaactacaa tgctggagac agaagcactg attatgggat atttcagatc
     2341 aatagccgct actggtgtaa tgatggcaaa accccaggag cagttaatgc ctgtcattta
     2401 tcctgcagtg gtaagacaag ctaatatttg accaatctgg ttatacttac aagaattgag
     2461 actcaataca aatgaaaaag ccttgaaagg ttcatgaggg acctagaaaa actacatctc
     2521 aacttccaga aagtcattat tattttcctc ataattccct gagtaagaaa tttaaagaag
     2581 tggtatcata aaaggttgat gttttttaat atacagaagt ttctggaatg acctattaat
     2641 ttactgtcaa tggccttact gatgctttgt ccagaacaat gccattgctc ctgcttactt
     2701 tggggaggtt ttgggataat ttagttgtat ggtccttttt caattgtttt actttttttt
     2761 ttatgaaatg ttctaaatgt atagaaaatt agagacatta gtataataaa cagccatatg
     2821 cccattatgc actttaaaag ttgttaacat tttgccatag ttgcttcttc tatgcctttt
     2881 tttttttttt tttttttttt tgctgagagt tttttgtttg gttttgtttt gttttatttt
     2941 gagacagggt ctcctgtccc caggctgtag tcagtggcac catcacagct cactgcagct
     3001 caagtgatca tcccaccaca gcctcccaag tagctgggac tacaggtgtg caccaccatg
     3061 cctggcaaat ttttgaaatt tttagtacag gcaaattctg tgttgcccag gctggtcttg
     3121 aactcctgag ttcaagcaat cttcccacct cagcctcctt aagctgctgg aattacaggc
     3181 gttagcactg tacctggcta ctgctgagag acttttaagt gaattaggaa catgatgata
     3241 ttccatttct aaattcttta gtttacatct tcaaaaaata cagttcctgt agaattatta
     3301 ttgtaaataa caaattaact taaggattta tttatttgga gtgaaacaaa tattttactg
     3361 aactcataaa aatagaaata ccatgtggaa tcctcagtgt caaaaatatt gcagaaatct
     3421 tgcaaagttg atattattaa attgttaaat attaaaattc ccaataaaga acattaatct
     3481 tatttctaaa atccagttaa ttaaaaaaat ttatattata taataatatt tggtcattaa
     3541 ataaaaatta gaaaatacaa ataagaaaaa taacacccat aatcttacta cccagaggtt
     3601 tataaccatg ggtaaattct ggtatatatt cttccagaat gtatatcaat catgtgtatg
     3661 aatgttaaat tatatcatac acatataaac ccacatacaa acatgtaaat actgtgtgct
     3721 tttgcaaaaa ttaaattgta ttatacacac ggctttacaa tttgcttctt atcacacaaa
     3781 attatttgca tgtcagcaaa tacaaatcgg tttttaatga tcttttgctc cattttccag
     3841 atgagaaaaa aatacaaatc tgtatcatca ttttaaaaga atgactagaa ttttaatata
     3901 tgaatattct ataatttact gatccaattg ttactattga gcacttaggt tgtttccatt
     3961 tttccctcat aaattgctat gaatagcttt ttgtatacat ctttgggtgc atttcttatt
     4021 tcttttggat aaattttcaa taatagaact gctgagtaaa atatcactag gtgttttttt
     4081 acagtgtcta gtgcaaagaa gacctttaat cattttgtta atacttccag agcttccaat
     4141 gactttggta aatgaagaaa aaaatgcttc atttcatgct gaatgggaga gaatgaagag
     4201 agttttcccc aacaattaca catatatgga ctcatagaaa ataatatctt accattcttt
     4261 ccacagccta acagaaaaaa gctggctaaa cctaaattta aaataaaata tctattaaag
     4321 tttttattcc ttaccacctg tctttcagct ttgctgcaag ataacatcgc tgatgctgta
     4381 gcttgtgcaa agagggttgt ccgtgatcca caaggcatta gagcatggta tgttttaagt
     4441 gttaaaaggg aaaactatct tactctactg ttgatatata caatgagagc agacttttaa
     4501 agaccaaagt atgctaatga cacctcaaaa ttgcagcttt tggcttatgc taaatgatgt
     4561 attacctaca tccttgaaga aacaatctac tttaactgat ccagaatctt actcttttac
     4621 tcctcaattt attttagggg atttctagag ttttaagatg cttcacactc tatcagttcc
     4681 ttgtcatatc ttgaaattct ttttagaata agtaagtgtg ggccgggcac agtgctcacg
     4741 cctgtaatcc cagcactttg ggagaccgag gcagatggat cacctgaggt caggagttcg
     4801 agaccagcct gcctaacatg gcaaaacccc atctccacta aaaatacaaa aaattagctg
     4861 ggtgtggtgc aggtgcctgt aatcccagcc actcgggagg ctgaggcagg agacttgctt
     4921 gaacccggga ggtggaggtt gcagaggatt gcgccattgt acttcagcct gggcgacaga
     4981 gtgagactct gtctcaaata aatagcataa aaaataaacg tggaattcac tttgcagttg
     5041 ctgctgtaca acgcacatta ctcaatcttt atgttcggca ttctatgctc tactgagaaa
     5101 tttgggtagg agtgaagtat tttgtataca tatcttcatt taataaatag caatagctgg
     5161 gtctatctta ctattttatc tattgataaa atattttgtt tccccaagga gtgcgaagta
     5221 tgtatattac aatgaagata tgttttaacc tttcaccatt tgcttcatct ttttctacag
     5281 ggtggcatgg agaaatcgtt gtcaaaacag agatgtccgt cagtatgttc aaggttgtgg
     5341 agtgtaactc cagaattttc cttcttcagc tcattttgtc tctctcacat taagggagta
     5401 ggaattaagt gaaaggtcac actaccatta tttccccttc aaacaaataa tatttttaca
     5461 gaagcaggag caaaatatgg cctttcttct aagagatata atgttcacta atgtggttat
     5521 tttatattaa gcctacaaca tttttcagtt tgcaaataga actaatactg gtgaaaattt
     5581 acctaaaacc ttggttatca aatacatctc cagtacattc cgttcttttt tttttttttt
     5641 tttttttttg agacagtctc gctctgtcgc ccaggctgga gtgcagtggc gcaatctcgg
     5701 ctcactgcaa cctccacctc ccgggttcac gccattctcc tgcctcagcc tcccgagtag
     5761 ctgggattac gggcgcccgc caccacgccc ggctaatttt ttgtattttt agtagagaca
     5821 gggtttcacc gtgttagcca ggatggtctc gatctcctga ccttgtgatc cacccacctc
     5881 ggcctcccaa agtgctggga ttacaggcgt gagccactgc gcccggccac attcagttct
     5941 tatcaaagaa ataacccaga cttaatcttg aatgatacga ttatgcccaa tattaagtaa
     6001 aaaatataag aaaaggttat cttaaataga tcttaggcaa aataccagct gatgaaggca
     6061 tctgatgcct tcatctgttc agtcatctcc aaaaacagta aaaataacca ctttttgttg
     6121 ggcaatatga aatttttaaa ggagtagaat accaaatgat agaaacagac tgcctgaatt
     6181 gagaattttg attttttaaa gtgtgtttct ttctaaattg ctgttcctta atttgattaa
     6241 tttaattcat gtattatgat taaatctgag gcagatgagc ttacaagtat tgaaataatt
     6301 actaattaat cacaaatgtg aagttatgca tgatgtaaaa aatacaaaca ttctaattaa
     6361 aggctttgca acacatgcct tgtctgtttt tatttagact cctatagtgt ctctgaagaa
     6421 aagaatacag atatttgaaa aaatatgatt tggtgctctt aatatctctt atatcgtcac
     6481 ttacctcact taaatagtca gatattgctg gagaaaaatt cacaagcatg ctgacaggtc
     6541 tcactttaaa ttcataacca taaatctcaa atgagccctc aagtctgcct gaccatttta
     6601 gttacttctc tacaatcctt ccatttttat gtccctagtc tccaaaatga ctgttactat
     6661 tttacttttc ctcttctctc ttcaaagcct caagacacac attcagcctc ctcctctgcc
     6721 cccttatcct ccaccctcct ctgctctcag cagataaact ggcctcatat tacacttcta
     6781 aaacaaaagc aacttcatac caagctt
//