H. sapiens amino acid sequence used shown in bold.
LOCUS HSLYSOZY 6807 bp DNA PRI 25-JUN-1997
DEFINITION Human lysozyme gene (EC 3.2.1.17).
ACCESSION X14008
NID g34433
KEYWORDS Alu repetitive sequence; lysozyme; repetitive sequence.
SOURCE human.
ORGANISM Homo sapiens
Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
Vertebrata; Mammalia; Eutheria; Primates; Catarrhini; Hominidae;
Homo.
REFERENCE 1 (bases 1 to 6807)
AUTHORS Sippel,A.E.
TITLE Direct Submission
JOURNAL Submitted (18-JAN-1989) Sippel A.E., ZMBH, Im Neuenheimer Feld 282,
D-6900 Heidelberg, FRG
REFERENCE 2 (bases 1 to 6807)
AUTHORS Peters,C.W., Kruse,U., Pollwein,R., Grzeschik,K.H. and Sippel,A.E.
TITLE The human lysozyme gene. Sequence organization and chromosomal
localization
JOURNAL Eur. J. Biochem. 182 (3), 507-516 (1989)
MEDLINE 89325294
COMMENT for human lysozyme mRNAs see M19045, J03801 and M21119. Data kindly
reviewed (21-AUG-1989) by Sippel A. E.
FEATURES Location/Qualifiers
source 1..6807
/organism="Homo sapiens"
/db_xref="taxon:9606"
/clone="lambda HLYS1."
/clone_lib="lambda EMBL3"
/chromosome="12"
TATA_signal 491..496
exon 519..682
/number=1
prim_transcript 519..6374
mRNA join(519..682,2246..2410,4349..4427,5281..6374)
sig_peptide 547..600
CDS join(601..682,2246..2410,4349..4427,5281..5347)
/EC_number="3.2.1.17"
/note="Protein sequence is in conflict with the conceptual
translation."
/codon_start=1
/product="lysozyme"
/db_xref="PID:e74526"
/db_xref="PID:g1335210"
/db_xref="SWISS-PROT:P00695"
/translation="KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNTRATN
YNAGDRSTDYGIFQINSRYWCNDGKTPGAVNACHLSCSALLQDNIADAVACAKRVVRD
PQGIRAWVAWRNRCQNRDVRQYVQGCGV"
intron 683..2245
/number=1
misc_feature 1120..1440
/note="Alu repetitive sequence"
exon 2246..2410
/number=2
intron 2411..4348
/number=2
misc_feature 2910..3199
/note="Alu repetitive sequence"
exon 4349..4427
/number=3
intron 4428..5280
/number=3
misc_feature 4721..4996
/note="Alu repetitive sequence"
exon 5281..6374
/number=4
misc_feature 5626..5928
/note="Alu repetitive sequence"
BASE COUNT 2090 a 1276 c 1204 g 2237 t
ORIGIN
1 tctagagtaa gaaactagct gagcaacgtg gtgtcacact atacacccat taagacaaca
61 ggcacatgtg tcatgtccat tttgtggaaa agatatgtaa aataatttta agtaaaaaag
121 ataaatataa aaaagtgaat gcatacaaaa caatttcaca aaattgaatg ttactcaaaa
181 atcacagctc attttaagct gcacaaaata gtcatttttt tctttataat tgctcaaatt
241 cataatcaaa cagaagaaag ttcctgtctt ggaagtagtg ctatgcccca attcttccag
301 agccagtact ttaaacaatt ccatttcatt attttcctgt agactaattc ttaggacatc
361 agcatatctc tcttcaagca ttaaaaaaat ctctttagag tcagtggatc aatagacagt
421 tcctgttttc cacacaactg aaagggtgga gcccccaaac cacaagggga agaaggaagt
481 taaaagatgt taaatactgg ggccagctca ccctggtcag cctagcactc tgacctagca
541 gtcaacatga aggctctcat tgttctgggg cttgtcctcc tttctgttac ggtccagggc
601 aaggtctttg aaaggtgtga gttggccaga actctgaaaa gattgggaat ggatggctac
661 aggggaatca gcctagcaaa ctgtaagtct actctccata attccagaga attagctacg
721 tatggaacag acactaggag agaaggaaga agaagaaggg gctttgagtg aatagatgtt
781 ttatttcttt gtgggtttgt atacttacaa tggctaaaaa catcagtttg gttctttata
841 accagagata cccgataaag gaatacgggc atggcagggg aaaattccat tctaagtaaa
901 acaggacctg ttgtactgtt ctagtgctag gaagtttgct gggtgcctga gattcaatgg
961 cacatgtaag ctgactgaaa gatacatttg aggacctggc agagctctct caagtccttg
1021 gtatgtgact ccagttattt cccattttga acttgggctc tgagagccta gagtgatgca
1081 gtatttttct tgtcttcaag tcccctgccg tgatgtggga tttttatttt tatttttatt
1141 ttattttatt ttatttttaa agacagtctc actgtgtggc ccaggctgga gtgcagtggc
1201 atgatctcag ctcactgcaa cctctgcctt ctgggctcaa gtgattctcg tgcttcagcc
1261 ttctgagtag ctgtgactac aggtgtgtac caccacaccc agctaatttt ttgtattttc
1321 agtagagatg gggtttcacc atgttggcca agctggtctt gaactcctgg cctcaaatga
1381 tctgcccacc tcagcctccc aaagtggtag gattacaggt gtgaaccact gcacccagcc
1441 gacatgggat ttttaacagt gatgttttta aagaatatat tgaattccct acacaagagc
1501 agtaggaacc tagttccctt cagtcactct ttgtatagga tcccagaaac tcagcatgaa
1561 atgttttatt atttttatct actctacttg attaactatc tttcattttc tcccacacaa
1621 ttcaagatgt gccatgagga aaagttattt tatagtttag tacatagttg tcgatgtaat
1681 aatctctgta gttttcagat tgaattcaga catttcccct caatagctat ttttgaatga
1741 atgagtgaag ggatgaaatc acggaatagt cttgttttca agattctaac ttgatatcca
1801 aattcacctt tagatattat aagaaaattt ctatcagaaa atccttatgt ttttctgatt
1861 aaaaaaagca tttttccatc agcctatgta tctgctatga atttacaaaa tctactcaac
1921 agctctgttg atttttctgt tcttggctga atgttgcctg agggatggga gcacgggaag
1981 ggtaaaagca atggaagaaa catgtatttt aatattttaa aagtatgtta tattgttcgt
2041 tggtgttaca agatgatttg cattacaaaa ggattctctt acaagtccct tatcttaaca
2101 ctaaagtgct aagatatttt ataagtaaat ctttatactt ataaaacaaa tcagtaaaat
2161 agaagtagct aagtagaact gattttgcta tagagtataa gtcacttagt gttgctgttt
2221 attactaaaa ataagttctt ttcagggatg tgtttggcca aatgggagag tggttacaac
2281 acacgagcta caaactacaa tgctggagac agaagcactg attatgggat atttcagatc
2341 aatagccgct actggtgtaa tgatggcaaa accccaggag cagttaatgc ctgtcattta
2401 tcctgcagtg gtaagacaag ctaatatttg accaatctgg ttatacttac aagaattgag
2461 actcaataca aatgaaaaag ccttgaaagg ttcatgaggg acctagaaaa actacatctc
2521 aacttccaga aagtcattat tattttcctc ataattccct gagtaagaaa tttaaagaag
2581 tggtatcata aaaggttgat gttttttaat atacagaagt ttctggaatg acctattaat
2641 ttactgtcaa tggccttact gatgctttgt ccagaacaat gccattgctc ctgcttactt
2701 tggggaggtt ttgggataat ttagttgtat ggtccttttt caattgtttt actttttttt
2761 ttatgaaatg ttctaaatgt atagaaaatt agagacatta gtataataaa cagccatatg
2821 cccattatgc actttaaaag ttgttaacat tttgccatag ttgcttcttc tatgcctttt
2881 tttttttttt tttttttttt tgctgagagt tttttgtttg gttttgtttt gttttatttt
2941 gagacagggt ctcctgtccc caggctgtag tcagtggcac catcacagct cactgcagct
3001 caagtgatca tcccaccaca gcctcccaag tagctgggac tacaggtgtg caccaccatg
3061 cctggcaaat ttttgaaatt tttagtacag gcaaattctg tgttgcccag gctggtcttg
3121 aactcctgag ttcaagcaat cttcccacct cagcctcctt aagctgctgg aattacaggc
3181 gttagcactg tacctggcta ctgctgagag acttttaagt gaattaggaa catgatgata
3241 ttccatttct aaattcttta gtttacatct tcaaaaaata cagttcctgt agaattatta
3301 ttgtaaataa caaattaact taaggattta tttatttgga gtgaaacaaa tattttactg
3361 aactcataaa aatagaaata ccatgtggaa tcctcagtgt caaaaatatt gcagaaatct
3421 tgcaaagttg atattattaa attgttaaat attaaaattc ccaataaaga acattaatct
3481 tatttctaaa atccagttaa ttaaaaaaat ttatattata taataatatt tggtcattaa
3541 ataaaaatta gaaaatacaa ataagaaaaa taacacccat aatcttacta cccagaggtt
3601 tataaccatg ggtaaattct ggtatatatt cttccagaat gtatatcaat catgtgtatg
3661 aatgttaaat tatatcatac acatataaac ccacatacaa acatgtaaat actgtgtgct
3721 tttgcaaaaa ttaaattgta ttatacacac ggctttacaa tttgcttctt atcacacaaa
3781 attatttgca tgtcagcaaa tacaaatcgg tttttaatga tcttttgctc cattttccag
3841 atgagaaaaa aatacaaatc tgtatcatca ttttaaaaga atgactagaa ttttaatata
3901 tgaatattct ataatttact gatccaattg ttactattga gcacttaggt tgtttccatt
3961 tttccctcat aaattgctat gaatagcttt ttgtatacat ctttgggtgc atttcttatt
4021 tcttttggat aaattttcaa taatagaact gctgagtaaa atatcactag gtgttttttt
4081 acagtgtcta gtgcaaagaa gacctttaat cattttgtta atacttccag agcttccaat
4141 gactttggta aatgaagaaa aaaatgcttc atttcatgct gaatgggaga gaatgaagag
4201 agttttcccc aacaattaca catatatgga ctcatagaaa ataatatctt accattcttt
4261 ccacagccta acagaaaaaa gctggctaaa cctaaattta aaataaaata tctattaaag
4321 tttttattcc ttaccacctg tctttcagct ttgctgcaag ataacatcgc tgatgctgta
4381 gcttgtgcaa agagggttgt ccgtgatcca caaggcatta gagcatggta tgttttaagt
4441 gttaaaaggg aaaactatct tactctactg ttgatatata caatgagagc agacttttaa
4501 agaccaaagt atgctaatga cacctcaaaa ttgcagcttt tggcttatgc taaatgatgt
4561 attacctaca tccttgaaga aacaatctac tttaactgat ccagaatctt actcttttac
4621 tcctcaattt attttagggg atttctagag ttttaagatg cttcacactc tatcagttcc
4681 ttgtcatatc ttgaaattct ttttagaata agtaagtgtg ggccgggcac agtgctcacg
4741 cctgtaatcc cagcactttg ggagaccgag gcagatggat cacctgaggt caggagttcg
4801 agaccagcct gcctaacatg gcaaaacccc atctccacta aaaatacaaa aaattagctg
4861 ggtgtggtgc aggtgcctgt aatcccagcc actcgggagg ctgaggcagg agacttgctt
4921 gaacccggga ggtggaggtt gcagaggatt gcgccattgt acttcagcct gggcgacaga
4981 gtgagactct gtctcaaata aatagcataa aaaataaacg tggaattcac tttgcagttg
5041 ctgctgtaca acgcacatta ctcaatcttt atgttcggca ttctatgctc tactgagaaa
5101 tttgggtagg agtgaagtat tttgtataca tatcttcatt taataaatag caatagctgg
5161 gtctatctta ctattttatc tattgataaa atattttgtt tccccaagga gtgcgaagta
5221 tgtatattac aatgaagata tgttttaacc tttcaccatt tgcttcatct ttttctacag
5281 ggtggcatgg agaaatcgtt gtcaaaacag agatgtccgt cagtatgttc aaggttgtgg
5341 agtgtaactc cagaattttc cttcttcagc tcattttgtc tctctcacat taagggagta
5401 ggaattaagt gaaaggtcac actaccatta tttccccttc aaacaaataa tatttttaca
5461 gaagcaggag caaaatatgg cctttcttct aagagatata atgttcacta atgtggttat
5521 tttatattaa gcctacaaca tttttcagtt tgcaaataga actaatactg gtgaaaattt
5581 acctaaaacc ttggttatca aatacatctc cagtacattc cgttcttttt tttttttttt
5641 tttttttttg agacagtctc gctctgtcgc ccaggctgga gtgcagtggc gcaatctcgg
5701 ctcactgcaa cctccacctc ccgggttcac gccattctcc tgcctcagcc tcccgagtag
5761 ctgggattac gggcgcccgc caccacgccc ggctaatttt ttgtattttt agtagagaca
5821 gggtttcacc gtgttagcca ggatggtctc gatctcctga ccttgtgatc cacccacctc
5881 ggcctcccaa agtgctggga ttacaggcgt gagccactgc gcccggccac attcagttct
5941 tatcaaagaa ataacccaga cttaatcttg aatgatacga ttatgcccaa tattaagtaa
6001 aaaatataag aaaaggttat cttaaataga tcttaggcaa aataccagct gatgaaggca
6061 tctgatgcct tcatctgttc agtcatctcc aaaaacagta aaaataacca ctttttgttg
6121 ggcaatatga aatttttaaa ggagtagaat accaaatgat agaaacagac tgcctgaatt
6181 gagaattttg attttttaaa gtgtgtttct ttctaaattg ctgttcctta atttgattaa
6241 tttaattcat gtattatgat taaatctgag gcagatgagc ttacaagtat tgaaataatt
6301 actaattaat cacaaatgtg aagttatgca tgatgtaaaa aatacaaaca ttctaattaa
6361 aggctttgca acacatgcct tgtctgtttt tatttagact cctatagtgt ctctgaagaa
6421 aagaatacag atatttgaaa aaatatgatt tggtgctctt aatatctctt atatcgtcac
6481 ttacctcact taaatagtca gatattgctg gagaaaaatt cacaagcatg ctgacaggtc
6541 tcactttaaa ttcataacca taaatctcaa atgagccctc aagtctgcct gaccatttta
6601 gttacttctc tacaatcctt ccatttttat gtccctagtc tccaaaatga ctgttactat
6661 tttacttttc ctcttctctc ttcaaagcct caagacacac attcagcctc ctcctctgcc
6721 cccttatcct ccaccctcct ctgctctcag cagataaact ggcctcatat tacacttcta
6781 aaacaaaagc aacttcatac caagctt
//