LOCUS 547968 1853 aa 01-NOV-1997
DEFINITION DILUTE MYOSIN HEAVY CHAIN, NON-MUSCLE (MYOSIN 5A).
ACCESSION 547968 PID g547968 DB
SOURCE SWISS-PROT: locus MY5A_MOUSE, accession Q99104 class: standard. created: Jun 1, 1994. sequence updated: Jun 1, 1994. annotation updated: Nov 1, 1997. xrefs: gi: 50714, gi: 50715, gi: 476354 xrefs (non-sequence databases): MGD MGI:105976
KEYWORDS MYOSIN; REPEAT; ATP-BINDING; CALMODULIN-BINDING; ACTIN-BINDING; HEPTAD REPEAT PATTERN; COILED COIL; PHOSPHORYLATION.
SOURCE house mouse.
ORGANISM Mus musculus Eukaryotae; Metazoa; Chordata; Vertebrata; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE 1 (residues 1 to 1853)
AUTHORS Mercer,J.A., Seperack,P.K., Strobel,M.C., Copeland,N.G. and Jenkins,N.A.
TITLE Novel myosin heavy chain encoded by murine dilute coat colour locus
JOURNAL Nature 349 (6311), 709-713 (1991)
MEDLINE 91141583
REMARK SEQUENCE FROM N.A. STRAIN=C57BL/6; TISSUE=BRAINErratum:[[published erratum appears in Nature 1991 Aug 8;352(6335):547]]
REFERENCE 2 (residues 1 to 1853)
AUTHORS MERCER,J.A., SEPERACK,P.K., STROBEL,M.C., COPELAND,N.G. and JENKINS,N.A.
JOURNAL NATURE 352, 547-547 (1991)
REMARK REVISIONS. COMMENT [FUNCTION] MAY BE INVOLVED IN MELANOSOME TRANSPORT, OR ALTERNATIVELY, IT MAY BE REQUIRED FOR SOME POLARIZATION PROCESS INVOLVED IN DENDRITE FORMATION. [SUBUNIT] MAY BE A HOMODIMER, WHICH ASSOCIATES WITH MULTIPLE CALMODULIN OR MYOSIN LIGHT CHAINS. [SIMILARITY] BELONGS TO CLASS-5 MYOSINS.
FEATURES Location/Qualifiers source 1..1853 /organism="Mus musculus" /db_xref="taxon:10090" 1..1853 Region 1..765 /note="HEAD." /region_name="Domain" Protein 1..1853 /product="DILUTE MYOSIN HEAVY CHAIN, NON-MUSCLE" Site 163..170 /note="ATP." /site_type="np-binding" Region 643..665 /note="ACTIN-BINDING." /region_name="Domain" Region 766..790 /note="1." /region_name="Repetitive region" Region 766..913 /note="NECK." /region_name="Domain" Region 766..887 /note="5 X APPROXIMATE TANDEM REPEATS." /region_name="Domain" Region 773..787 /note="CALMODULIN-BINDING." /region_name="Domain" Region 791..815 /note="2." /region_name="Repetitive region" Region 796..810 /note="CALMODULIN-BINDING." /region_name="Domain" Region 816..837 /note="3." /region_name="Repetitive region" Region 821..835 /note="CALMODULIN-BINDING." /region_name="Domain" Region 838..863 /note="4." /region_name="Repetitive region" Region 844..862 /note="CALMODULIN-BINDING." /region_name="Domain" Region 864..888 /note="5." /region_name="Repetitive region" Region 869..884 /note="CALMODULIN-BINDING." /region_name="Domain" Region 892..906 /note="CALMODULIN-BINDING." /region_name="Domain" Region 914..1040 /note="COILED COIL." /region_name="Domain" Region 1041..1853 /note="TAIL." /region_name="Domain" Site 1758 /site_type="phosphorylation"
ORIGIN 1 maaselytkf arvwipdpee vwksaellkd ykpgdkvlll hleegkdley rldpktgelp 61 hlrnpdilvg endltalsyl hepavlhnlr vrfidskliy tycgivlvai npyeqlpiyg 121 ediinaysgq nmgdmdphif avaeeaykqm ardernqsii vsgesgagkt vsakyamryf 181 atvsgsasea nveekvlasn pimesignak ttrndnssrf gkyieigfdk ryriiganmr 241 tylleksrvv fqaeeernyh ifyqlcasak lpefkmlrlg nadsfhytkq ggspmiegvd 301 dakemahtrq actllgises yqmgifrila gilhlgnvgf asrdsdscti ppkhepltif 361 cdlmgvdyee mchwlchrkl atatetyikp isklqatnar dalakhiyak lfnwivdhvn 421 qalhsavkqh sfigvldiyg fetfeinsfe qfcinyanek lqqqfnmhvf kleqeeymke 481 qipwtlidfy dnqpcinlie sklgildlld eeckmpkgtd dtwaqklynt hlnkcalfek 541 prmsnkafii khfadkveyq cegfleknkd tvfeeqikvl ksskfkmlpe lfqddekais 601 ptsatssgrt pltrvpvkpt kgrpgqtake hkktvghqfr nslhllmetl nattphyvrc 661 ikpndfkfpf tfdekravqq lracgvleti risargfpsr wtyqeffsry rvlmkqkdvl 721 gdrkqtcknv leklildkdk yqfgktkiff ragqvaylek lradklraac iriqktirgw 781 llrkrylcmq raaitvqryv rgyqarcyak flrrtkaatt iqkywrmyvv rrrykirraa 841 tiviqsylrg yltrnryrki lreykaviiq krvrgwlart hykrtmkaiv ylqccfrrmm 901 akrdvkklki earsverykk lhigmenkim qlqrkvdeqn kdykclmekl tnlegvynse 961 teklrndver lqlseeeakv atgrvlslqe eiaklrkdle qtrsekksie eradkykqet 1021 dqlvsnlkee ntllkqeket lnhriveqak emtetmerkl veetkqleld lnderlryqn 1081 llnefsrlee ryddlkeemt lmlnvpkpgh krtdsthssn eseytfssef aetediaprt 1141 eepiekkvpl dmslflklqk rvteleqekq lmqdeldrke eqvfrskake eerpqirgae 1201 leyeslkrqe lesenkklkn elnelrkals eksapevtap gapayrvlme qltsvseeld 1261 vrkeevlilr sqlvsqkeai qpkddkntmt dstilledvq kmkdkgeiaq ayiglketnr 1321 llesqlqsqk rsheneaeal rgeiqslkee nnrqqqllaq nlqlppeari easlqheitr 1381 ltnenlyfee lyaddpkkyq syrislykrm idlmeqlekq dktvrklkkq lkvfakkige 1441 levgqmenis pgqiidepir pvniprkekd fqgmleykre deqklvknli lelkprgvav 1501 nlipglpayi lfmcvrhady lnddqkvrsl ltstinsikk vlkkrgddfe tvsfwlsntc 1561 rflhclkqys geegfmkhnt srqnehcltn fdlaeyrqvl sdlaiqiyqq lvrvlenilq 1621 pmivsgmleh etiqgvsgvk ptglrkrtss iadegtytld silrqlnsfh svmcqhgmdp 1681 elikqvvkqm fyivgaitln nlllrkdmcs wskgmqiryn vsqleewlrd knlmnsgake 1741 tlepliqaaq llqvkkktdd daeaicsmcn alttaqivkv lnlytpvnef eervsvsfir 1801 tiqmrlrdrk dspqllmdak hifpvtfpfn psslaletiq ipaslglgfi arv //