LOCUS HSP53R 2066 bp RNA PRI 27-JAN-1995
DEFINITION Human mRNA fragment for phosphoprotein p53.
ACCESSION X01405
NID g35215
KEYWORDS Alu repetitive sequence; antigen; phosphoprotein; tumor antigen.
SOURCE human.
ORGANISM Homo sapiens
Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2066)
AUTHORS Matlashewski,G., Lamb,P., Pim,D., Peacock,J., Crawford,L. and
Benchimol,S.
TITLE Isolation and characterization of a human p53 cDNA clone:
expression of the human p53 gene
JOURNAL EMBO J. 3 (13), 3257-3262 (1984)
MEDLINE 85126934
REFERENCE 2 (bases 1 to 2066)
AUTHORS Crawford,L.
TITLE Direct Submission
JOURNAL Submitted (06-NOV-1985) to the EMBL/GenBank/DDBJ databases
COMMENT Data kindly reviewed (06-NOV-1985)) by Crawford L.
FEATURES Location/Qualifiers
source 1..2066
/organism="Homo sapiens"
/db_xref="taxon:9606"
CDS <1..883
/codon_start=2
/product="p53"
/db_xref="PID:g642241"
/db_xref="SWISS-PROT:P04637"
/translation="KTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQ
LWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLR
VEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDS
SGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQP
KKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQS
TSRHKKLMFKTEGPDSD"
old_sequence 1375..1379
/note="aacuu was au in [1]"
/citation=[1]
old_sequence 1392..1394
/note="ggu was gu in [1]"
/citation=[1]
misc_feature 1626..1936
/note="Alu-repeat sequence"
misc_feature 2049..2054
/note="pot. polyA signal"
polyA_site 2066
/note="polyA site"
BASE COUNT 445 a 568 c 509 g 544 t
ORIGIN
1 caaaacctac cagggcagct acggtttccg tctgggcttc ttgcattctg ggacagccaa
61 gtctgtgact tgcacgtact cccctgccct caacaagatg ttttgccaac tggccaagac
121 ctgccctgtg cagctgtggg ttgattccac acccccgccc ggcacccgcg tccgcgccat
181 ggccatctac aagcagtcac agcacatgac ggaggttgtg aggcgctgcc cccaccatga
241 gcgctgctca gatagcgatg gtctggcccc tcctcagcat cttatccgag tggaaggaaa
301 tttgcgtgtg gagtatttgg atgacagaaa cacttttcga catagtgtgg tggtgcccta
361 tgagccgcct gaggttggct ctgactgtac caccatccac tacaactaca tgtgtaacag
421 ttcctgcatg ggcggcatga accggaggcc catcctcacc atcatcacac tggaagactc
481 cagtggtaat ctactgggac ggaacagctt tgaggtgcgt gtttgtgcct gtcctgggag
541 agaccggcgc acagaggaag agaatctccg caagaaaggg gagcctcacc acgagctgcc
601 cccagggagc actaagcgag cactgcccaa caacaccagc tcctctcccc agccaaagaa
661 gaaaccactg gatggagaat atttcaccct tcagatccgt gggcgtgagc gcttcgagat
721 gttccgagag ctgaatgagg ccttggaact caaggatgcc caggctggga aggagccagg
781 ggggagcagg gctcactcca gccacctgaa gtccaaaaag ggtcagtcta cctcccgcca
841 taaaaaactc atgttcaaga cagaagggcc tgactcagac tgacattctc cacttcttgt
901 tccccactga cagcctccca cccccatctc tccctcccct gcgattttgg gttttgggtc
961 tttgaaccct tgcttgcaat aggtgtgcgt cagaagcacc caggacttcc atttgctttg
1021 tcccggggct ccactgaaca agttggcctg cactggtgtt ttgttgtggg gaggaggatg
1081 gggagtagga cataccagct tagattttaa ggtttttact gtgagggatg tttgggagat
1141 gtaagaaatg ttcttgcagt taagggttag tttacaatca gccacattct aggtaggggc
1201 ccacttcacc gtactaacca gggaagctgt ccctcactgt tgaattttct ctaacttcaa
1261 ggcccatatc tgtgaaatgc tggcatttgc acctacctca cagagtgcat tgtgagggtt
1321 aatgaaataa tgtacatctg gccttgaaac caccttttat tacatggggt ctagaacttg
1381 acccccttga gggtgcttgt tccctctccc tgttggtcgg tgggttggta gtttctacag

1441 ttgggcagct ggttaggtag agggagttgt caagtctctg ctggcccagc caaaccctgt
1501 ctgacaacct cttggtgaac cttagatcct aaaaggaaat gtcaccccat cccacaccct
1561 ggaggatttc atctcttgta tagatgatct ggatccacca agacttgttt tagctcaggg
1621 tccaatttct tttttctttt tttttttttt tttctttttc tttgagactg ggtctctttg
1681 ttgccccagg ctggagtgga gtggcgtgat ctggcttact gcagcctttg cctccccggc
1741 tcgagcagtc ctgcctcagc ctccggagta gctgggacca caggttcatg ccaccatggc
1801 cagccaactt ttgcatgttt tgtagagatg gggtctcaca gtgttgccca ggctggtctc
1861 aaactcctgg gctcaggcga tccacctgtc tcagcctccc agagtgctgg gattacaatt
1921 gtgagccacc acgtccagct ggaagggtca acatctttta cattctgcaa gcacatctgc
1981 attttcaccc cacccttccc ctcttctccc tttttatatc ccatttttat atcgatctct
2041 tattttacaa taaaactttg ctgcca
//