LOCUS HUMRECQ 2925 bp mRNA PRI 08-JAN-1995

DEFINITION Homo sapiens (clone 1311) DNA helicase (RECQL) mRNA, complete cds.

ACCESSION L36140 NID g619862

KEYWORDS DNA helicase.

SOURCE Homo sapiens cDNA to mRNA.

ORGANISM Homo sapiens

Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata; Vertebrata; Eutheria; Primates; Catarrhini; Hominidae; Homo.

REFERENCE 1 (bases 1 to 2925)

AUTHORS Puranam,K.L. and Blackshear,P.J.

TITLE Cloning and characterization of RECQL, a potential human homologue of the E. coli DNA helicase RecQ

JOURNAL J. Biol. Chem. 269, 29838-29845 (1994)

MEDLINE 95050841

FEATURES Location/Qualifiers source 1..2925 /organism="Homo sapiens" /db_xref="taxon:9606" /cell_line="HeLa" /clone="1311" gene 528..2507 /gene="RECQL" CDS 528..2507 /gene="RECQL" /note="homologue of E. Coli DNA helicase reqQ" /codon_start=1 /product="DNA helicase" /db_xref="PID:g619863" /

translation="MASVSALTEELDSITSELHAVEIQIQELTERQQELIQKKKVLTK KIKQCLEDSDAGASNEYDSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINV TMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATM LNASSSKEHVKWVHDEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAV DEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCIEKCFT FTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSL QNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMS KSMENYYQESGRAGRDDMKADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNI SKSRRVLMAQHFDEVWNSEACNKMCDNCCKDSAFERTNITEYCRDLIKILKQAEELNE KLTPLKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFTAYAA ISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRAESSQTCHSEQGDKKNGGKKIQATS RRRLQTCFSNLVLRIQELRKEKSMMPDMNVTKFSN"

BASE COUNT 934 a 486 c 641 g 864 t

ORIGIN

1 cttttttttt tttttttttt tttttataag attattagta taaaatttta gataggtagg 61 agtagcgaaa agatctgctc gaggcctggg tgctttggtg tcggagatcc gagagtcgga 121 gatcggagag tcggacacag gacagtcgga caccggacag tcaaacaccg gagagttaga 181 ctgggcttct cggtggggac aggctctggg ataactactg ttacagcttt gaagggtcaa 241 gggtgtgcgc tttttctttc atccttccct ttcctgctgc aggcgaggcc ggtctgatgc 301 ggatcacttc ctttcgccca cacattggcg gaggagaaac cggaaagtta atcactgccc 361 tgctctgaga actcgggcct ttaggggcac gttcgcctgc tgaccggtct tctgatctcc 421 ccattctttt ccatgcagga ggattggcca ccaaagcctg tttattagca gctgccattt 481 gttaaagaaa tttggattat tttagaaaca atttggaaag aaaaagaatg gcgtccgttt 541 cagctctaac tgaggaactg gattctataa ccagtgagct acatgcagta gaaattcaaa 601 ttcaagaact tacggaaagg caacaagagc ttattcagaa aaaaaaagtc ctgacaaaga 661 aaataaagca gtgtttagag gattctgatg ccggggcaag caatgaatat gattcttcac 721 ctgccgcttg gaataaagaa gattttccat ggtctggtaa agttaaagat attctgcaaa 781 atgtctttaa actggaaaag ttcagaccac ttcagcttga aactattaac gtaacaatgg 841 ctggaaagga ggtatttctt gttatgccta caggaggtgg aaagagctta tgttaccagt 901 taccagcatt atgttcagat ggttttacac tcgtcatttg cccattgatc tctcttatgg 961 aagaccaatt aatggtttta aaacaattag gaatttcagc aaccatgtta aatgcttcta 1021 gttctaagga gcatgttaaa tgggttcatg atgaaatggt aaataaaaac tccgagttaa 1081 agctgattta tgtgactcca gagaaaattg caaaaagcaa aatgtttatg tcaagactag 1141 agaaagccta tgaagcaagg agatttactc gaattgctgt ggatgaagtt cactgctgta 1201 gtcagtgggg acatgatttc agacctgatt ataaggcact tggtatctta aagcggcagt 1261 tccctaacgc atcactaatt gggctgactg caactgcaac aaatcacgtt ttgacggatg 1321 ctcagaaaat tttgtgcatt gaaaagtgtt ttacttttac agcttctttt aataggccaa 1381 atctatatta tgaggttcgg cagaagccct caaacactga agattttatt gaggatattg 1441 taaagctcat taatgggaga tacaaagggc aatcaggaat catatattgt ttttctcaga 1501 aagactctga acaagttacg gttagtttgc agaatctggg aattcatgca ggtgcttacc 1561 atgccaattt ggagccagaa gataagacca cagttcatag aaaatggtca gccaatgaaa 1621 ttcaggtagt agtggcaact gttgcatttg gtatgggaat tgataagcca gatgtgaggt 1681 ttgttatcca tcattcaatg agtaaatcca tggaaaatta ttaccaagag agtggacgtg 1741 caggtcgaga tgacatgaaa gcagactgta ttttgtacta cggctttgga gatatattca 1801 gaataagttc aatggtggtg atggaaaatg tgggacagca gaagctttat gagatggtat 1861 catactgtca aaacataagc aaatctcgtc gtgtgttgat ggctcaacat tttgatgaag 1921 tatggaactc agaagcatgt aacaaaatgt gcgataactg ctgtaaagac agtgcatttg 1981 aaagaacgaa cataacagag tactgcagag atctaatcaa gatcctgaag caggcagagg 2041 aactgaatga aaaactcact ccattgaaac tgattgattc ttggatggga aagggtgcag 2101 caaaactgag agtagcaggt gttgtggctc ccacacttcc tcgtgaagat ctggagaaga 2161 ttattgcaca ctttctaata cagcagtatc ttaaagaaga ctacagtttt acagcttatg 2221 ctgccatttc gtatttgaaa ataggaccta aagctaatct tctgaacaat gaggcacatg 2281 ctattactat gcaagtgaca aagtccacgc agaactcttt cagggctgaa tcgtctcaaa 2341 cttgtcattc tgaacaaggt gataaaaaga atggaggaaa aaaaattcag gcaacttcca 2401 gaagaaggct gcaaacatgc ttcagcaatc tggttctaag aatacaggag ctaagaaaag 2461 aaaaatcgat gatgcctgat atgaatgtta ctaaattttc taattaaaga tggtttatgc 2521 atgtatatgc cattattttt gtagttagac aatagttttt aaaagaattt catagatatt 2581 ttatatgtat ggatctatat tttcagagct tatctctgaa gatctaaact tttgagaatg 2641 tttgaaaatt agagatcatg aattatataa ttttccagtg taaaacaagg gaaaaatttt 2701 tatgtaaaac cctttaaatg taaaatattt gagaataagt tcatacaatc gtcttaagtt 2761 ttttatgcct ttatatactt agctatattt tttcttttga cataactatc tttttgaaag 2821 caatattata ctgacagagg cttcactgag tgatacttta agttaaatat gtagatcaag 2881 ggatgtccaa tcttttggct tccctgagcc agcgaattgt gcaca //