This page was created for an undergraduate course at Davidson College.
Picture taken from PDB, 1hex.
Title:
Structure of 3-isopropylmalate dehydrogenase in complex with NAD+:
ligand-induced loop closing and mechanism for cofactor specificity.
Compound:
3-Isopropylmalate Dehydrogenase (E.C. 1.1.1.85) Complexed With -Nicotinamide
Adenine Dinucleotide, Oxidized (Nad+)
Authors:
J. H. Hurley
Source:
not available
Primary Citation:
Hurley, J. H., Dean, A. M.: Structure of 3-isopropylmalate dehydrogenase in complex
with NAD+: ligand-induced loop closing and mechanism for cofactor specificity.
Structure 2 pp. 1007 (1994)
[ Medline ]
To manipulate the image:
PC: right click anywhere on the image to get a list of options
Mac: click and hold anywhere on the image to get a list of options
Try performing the following manipulations using the list of options:
1. Go to display -> cartoon
2. Go to select -> change color to -> purple
3. Go to select -> hetero -> ligand
4. Go to display -> ball and stick
5. Go to color -> CPK
6. Rotate the image by clicking on the mouse and moving the mouse around.
7. Orient the molecule so that you can see the NAD molecule.