LOCUS AF212319 1679 bp mRNA linear ROD 07-MAY-2001
DEFINITION Mus musculus NADP+-specific isocitrate dehydrogenase mRNA, complete
cds; nuclear gene for mitochondrial product.
ACCESSION AF212319
VERSION AF212319.1 GI:12003361
KEYWORDS .
SOURCE house mouse.
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE 1 (bases 1 to 1679)
AUTHORS Jo,S.H., Son,M.K., Koh,H.J., Lee,S.M., Song,I.H., Kim,Y.O.,
Lee,Y.S., Jeong,K.S., Kim,W.B., Park,J.W., Song,B.J. and Huhe,T.L.
TITLE Control of Mitochondrial Redox Balance and Cellular Defense against
Oxidative Damage by Mitochondrial NADP+-dependent Isocitrate
Dehydrogenase
JOURNAL J. Biol. Chem. 276 (19), 16168-16176 (2001)
PUBMED 11278619
REFERENCE 2 (bases 1 to 1679)
AUTHORS Huh,T.L., Jo,S.H. and Son,M.K.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-1999) Genetic Engineering, Kyungpook National
University, San-kyuk-dong 1370, Taegu 702-701, South Korea
FEATURES Location/Qualifiers
source 1..1679
/organism="Mus musculus"
/strain="3T3"
/db_xref="taxon:10090"
CDS 46..1404
/note="IDPm"
/codon_start=1
/product="NADP+-specific isocitrate dehydrogenase"
/protein_id="AAG43538.1"
/db_xref="GI:12003362"
/translation="MAGYLRAVSSLCRASGSARTWAPAALTVPSWPEQPRRHYAEKRI
KVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL
ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRL
VPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFPAGGVG
MGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKT
DFDRNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVL
VCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLI
RFAQTLEKVCVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG
KQ"
BASE COUNT 404 a 438 c 477 g 360 t
ORIGIN
1 cgcacagccc ggtgcagcgg cgtgctcgga cctcgcgtgc tcgggatggc cggctacctg
61 cgggctgtga gctcgctctg cagagcctcg ggctcagcgc ggacctgggc accggcagca
121 ctgactgtcc ccagctggcc ggagcagccg cggcgccact atgctgagaa gaggatcaag
181 gtggagaagc cggtagtgga gatggacggt gacgagatga cccggatcat ctggcagttc
241 atcaaggaga agctcatcct gcctcacgtg gatgttcagc tcaagtattt tgaccttggg
301 cttccaaacc gtgaccagac caatgaccag gtcaccattg actctgctct ggccacccag
361 aagtacagtg tggctgtcaa gtgtgccaca atcacccctg atgaggcccg tgtggaagag
421 ttcaagctga agaaaatgtg gaagagccct aacggaacga tccggaacat ccttggggga
481 accgtcttca gagagccaat catctgcaaa aacatccccc gccttgtccc tggctggacc
541 aagcccatca ccattggcag gcacgcccat ggcgaccagt acaaggccac agattttgtg
601 gtagatcgag ctggcacgtt caagttggtc ttcaccccaa aggatggcag cagtgccaag
661 gagtgggagg tgtataactt ccctgccgga ggcgttggga tggggatgta caacaccgac
721 gagtccattt cgggcttcgc gcacagctgc ttccagtact ctatccagaa gaaatggccg
781 ctctacttga gcaccaagaa caccattctg aaggcctatg acgggcgttt caaggacatc
841 ttccaggaga tctttgacaa gcactataag actgacttcg acaggaataa gatctggtat
901 gaacatcggc tcatcgacga catggtggcc caggtgctca agtcttccgg tggctttgtg
961 tgggcttgca aaaactatga tggagacgtg cagtctgaca tcctggctca aggctttggc
1021 tccctcggcc tgatgacatc tgtgctggtc tgccctgatg ggaagacaat tgaggctgag
1081 gctgctcatg ggacagtcac ccgccattac cgagaacacc agaagggccg gcccaccagt
1141 accaacccta ttgccagcat ctttgcctgg acacggggtc tggagcatcg tgggaagctg
1201 gatgggaacc aggaccttat caggtttgca cagacgctgg agaaggtgtg cgtgcagact
1261 gtggagagcg gagcgatgac caaggacctg gctggctgta tccatggcct cagcaatgtg
1321 aagctgaacg agcacttcct gaacaccaca gacttcctgg acaccattaa gagcaacctg
1381 gacagagctc tgggcaagca gtaggggtgg acactactca gctccagtgg gtactctgta
1441 catggcagag ggtgggcctc acagccctct ctggtggcct ttctagggac atttttttac
1501 atatatatat gatggagatg ttttttaaag tatatgagca ttttcctcac ggtggacatg
1561 aggcaggaac gtgtgcttta cctcagacag tcagtgttct gcatactgta atttatattg
1621 ctctggaatc acatggtgcc atatttagct actaaaaagc tcttcgcaaa aaaaaaaaa
//
Revised: October 24, 2001.