Gene Networks Database

SpEts4 - SpHE interaction

• REGULATOR: SpEts4
• TARGET: SpHE
• INTERACTION TYPE: protein-DNA
• INTERACTION RESULT: activation
• TISSUE: in vitro and 9-h nuclear extract
• STAGE:
• TARGET SITE: (C/A)GGA(A/T)
• PROOFS: EMSA results indicate that SpEts4 protein synthesized in vitro binds the SpHE -250 promoter element; identity of properties of complexes formed by binding of in vitro-translated protein and protein from 9-h nuclear extract to SpHE -250 promoter; mutation of the Ets cis element; linking the Ets site to the basal promoter; in vivo transcription via coinjected SpEts4 mRNA.
• REFERENCES: Wei et al., 1999
• COMMENTS: