Gene Networks Database

SpRunt1 - CyIIIa interaction

• REGULATOR: SpRunt1
• TARGET: CyIIIa
• INTERACTION TYPE: protein-DNA
• INTERACTION RESULT: activation
• TISSUE: aboral ectoderm
• STAGE: gastrula stage onward
• TARGET SITE:
• PROOFS: whole-mount in situ hybridization of the fusion constructs (1,2); EMSA, in vitro translation (2)
• REFERENCES: 1) Kirchhamer and Davidson, 1996; 2) Coffman et al., 1996
• COMMENTS: The spatial domain of SpRunt1 activity is inferred from the regions to which ectopic expression spreads when the target sites for interaction with the negative regulators of the middle module are deleted or mutated (Kirchhamer and Davidson, 1996).