Isocitrate Dehydrogenase (IDH) is a vital enzyme found in every cell. There are two major forms: NADP+-dependent (E.C. 1.1.1.42) and NAD+-dependent (E.C. 1.1.1.41). In the table below, you can see the range of IDH enzyme sequences we will analyze. The names in each box is the code used for the phylogenetic tree program. You can click on each code name and see the database entry used for this analysis.
Coenzyme
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Arabidopsis thaliana
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Caenorhabditis elegans
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Homo sapiens
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Saccharomyces cerevisiae
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Schizosaccharomyces pombe
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Escherichia coli
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Salmonella typhimurium
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Mycobacterium tuberculosis
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Mycobacterium leprae
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Methanococcus jannaschii
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Thermus aquaticus
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NADP+
1.1.1.42 |
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NAD+
1.1.1.41 |
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In order to create a phylogenetic tree, you first must align the amino acid sequences.
Or you can bypass seeing the alignment and just view the trees directly.
How these trees were produced.
If you are interested in creating other phylogenetic trees, you might try this ClustalW site at EBI.
© Copyright 2002 Department of Biology, Davidson College, Davidson,
NC 28035
Send comments, questions, and suggestions to: macampbell@davidson.edu