Create a Phylogenetic Tree


Isocitrate Dehydrogenase (IDH) is a vital enzyme found in every cell. There are two major forms: NADP+-dependent (E.C. 1.1.1.42) and NAD+-dependent (E.C. 1.1.1.41). In the table below, you can see the range of IDH enzyme sequences we will analyze. The names in each box is the code used for the phylogenetic tree program. You can click on each code name and see the database entry used for this analysis.

Coenzyme
Arabidopsis thaliana
Caenorhabditis elegans
Homo sapiens
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Escherichia coli
Salmonella typhimurium
Mycobacterium tuberculosis
Mycobacterium leprae
Methanococcus jannaschii
Thermus aquaticus
NADP+
1.1.1.42
NAD+
1.1.1.41

 

In order to create a phylogenetic tree, you first must align the amino acid sequences.

Or you can bypass seeing the alignment and just view the trees directly.

 

How these trees were produced.

If you are interested in creating other phylogenetic trees, you might try this ClustalW site at EBI.


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© Copyright 2002 Department of Biology, Davidson College, Davidson, NC 28035
Send comments, questions, and suggestions to: macampbell@davidson.edu