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This page was reviewed in Science, 7 March, 2003.
Vol. 299. pg. 1493.

Movies of Cells

Movies of Cellular Calcium

Movies of Molecular Methods

Molecular Movies - by A. Malcolm Campbell

These animations are made with the Macromedia program called Flash, and require the appropriate browser plug-in. These are standard features for 4.5 or newer browsers. These animations are being produced beginning in the summer of 1999 and are funded by a Mellon Technology Fellowship through the Associated Colleges of the South, and Davidson College's Summer Faculty Funding program.

Miscellaneous Movies

Interactive Pages

Credits (updates in progess)

Simultaneous imaging of an egg at fertilization by phase contrast (left) and Ca Green fluorescence (right). The fertilizing sperm can be seen at upper right contacting the egg. There is a Ca action potential around the entire egg surface (5 th frame), then several seconds later, the Ca wave starts at the site of sperm entry. The Ca wave triggers cortical granule exocytosis, leading to the formation of the fertilization envelope. The fertilization cone (primarily actin filaments) develops later at the sperm entry point. The first six frames of this sequence are at 0.5 sec intervals, while the remainder are at 1 sec intervals. movie

The competition of sperm to fertilize and pronuclei fusing were also from Mark Terasaki. A recent Video Essay was published in Molecular Biology of the Cell.

More animations and images can be found on the FlyBase page.

The maternal pronucleus migrates from the anterior to the posterior, through the pseudocleavage furrow. It meets the paternal pronucleus in the posterior and they migrate anteriorly before fusing and entering mitosis. During these events, P granules are organized from a dispersed state to the posterior cortex.

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