LOCUS
MUSALDAA 8190 bp DNA
ROD 27-APR-1993
DEFINITION Mouse aldolase A gene, complete cds.
ACCESSION J05517
VERSION J05517.1 GI:191872
KEYWORDS aldolase A.
SOURCE Mouse (strain RIII S/J and Blue Spruce
(outbred Swiss Webster))
adult DNA, clone lambda 16.
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE 1 (bases 1 to 8190)
AUTHORS Stauffer,J.K., Colbert,M.C. and Ciejek-Baez,E.M.
TITLE Nonconservative utilization of aldolase A
alternative promoters
JOURNAL J. Biol. Chem. 265, 11773-11782 (1990)
MEDLINE 90307699
COMMENT Draft entry and computer-readable sequence
for [1] kindly submitted
by J.K.Stauffer, 15-JUN-1990.
FEATURES
Location/Qualifiers
source 1..8190
/organism="Mus musculus"
/db_xref="taxon:10090"
TATA_signal 1673..1676
prim_transcript 1700..>6614
/note="aldolase A mRNA and introns (alt.)"
prim_transcript 1740..>6614
/note="aldolase A mRNA and introns (alt.)"
intron 1804..1951
/note="aldolase A intron A (put.); putative"
intron 2023..4278
/note="aldolase A intron B (put.); putative"
intron 2205..4278
/note="aldolase A intron C (alt.)"
TATA_signal 2235..2240
CAAT_signal 3032..3036
TATA_signal 3089..3094
TATA_signal 3132..3137
intron 3256..4278
/note="aldolase A intron C (alt.)"
CDS
join(4301..4412,4493..4704,5125..5179,5278..5438,
5727..5810,5908..6082,6222..6421,6519..6613)
/partial
/note="aldolase A"
/codon_start=1
/protein_id="AAA37210.1"
/db_xref="GI:553861"
/translation="MPHPYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRL
QSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKG
GVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPS
ALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALS
DHHVYLEGTLLKPNMVTPGHACTQKFSNEEIAMATVTALRRTVPPAVTXXXXXXXXXX
PWALTFSYGRALQASALKAWGGKKENLKAAQEEYIKRALANSLACQGKYTPSGQSGAA
ASESLFISNHAY"
exon
<4301..4412
/note="aldolase A, (E.C. 4.1.2.13) (first expressed
exon)"
/number=4
intron 4413..4492
/note="aldolase A intron D"
exon
4493..4704
/number=5
intron 4705..5124
/note="aldolase A intron E"
exon
5125..5179
/number=6
intron 5180..5277
/note="aldolase A intron F"
exon
5278..5438
/number=7
intron 5439..5726
/note="aldolase A intron G"
exon
5727..5810
/number=8
intron 5811..5907
/note="aldolase A intron H"
exon
5908..6082
/number=9
intron 6083..6221
/note="aldolase A intron I (no splice consensus);
putative"
exon
6222..6421
/number=10
intron 6422..6518
/note="aldolase A intron J"
exon
6519..>6614
/note="aldolase A"
/number=11
BASE COUNT 1676 a 1884 c
2061 g 1876 t 693 others
ORIGIN
1 gatccttgct ttttgaagcc ttagaatgaa gccagcattc ctggccttgg gagggcaggc
61 acgggagact ccaaggcctg gggaaagcaa ctctagtcca aaccagtttc tcttgctggt
121 tgtagtcttt tgggcaaacc actgagtttc tatctcatta ttttgtgatg agccccccac
181 gagtgtgacc cccattcaag gtggctcaga agcagagtgc ttgccttgtg tttgtgacat
241 cccaagttca attcatcact gaggaaaccc ctccctttaa gatttatctt atctctgaac
301 gttttcccga ttgtatgact cgtatgtatc tgaggaagtc agaagaaatg tcagatcccc
361 caggatcttg ggatctggag tcgtgatggc tgtgagtcac tgtatatatg tgctggagct
421 gaactcaggt cctctggaac agccattgct cttaaccact gagccatggt ccggacacct
481 ggcttagaca gggtcccttt ctgtcagtgg ttctcaacct gtgggttatg gccctttgtg
541 ggggtggagg tgggtattaa cttatacagg gctgacctaa ggttataaaa acccagatat
601 ttatgattca taacagcaaa attacaggtg taaagtagca acaaaaattc ttttttggtt
661 gggagtacca caacatgggg aactgtatta aaaggtagca ttaggaaggt tgggcaccac
721 tgctctcgta gccctggcta tcctagaact caaatagtag atcaggctgg tccaaactga
781 cagagatcta tctctgccag cgtcagcact aggaagtgag taaattccat gatagccagg
841 ccatacagtg aaaccctgtc tcaaaacagg acaagaggaa ccccagtact tagtaggttg
901 aagtaaggat tgtcattttt tttgaggcca gcttgggttt catggctctt gactagtctg
961 agctgtagag ggagagcctg tctcacgagg aagcttagga gggagatatt atagtttggt
1021 ttatgccagc aagaaagtcc aaagtcccag aaattatctt catgaggatt gaaacatgtt
1081 ttctggtcct gacttcctct aggttgcata gggctttgag agtatagtat acctactatg
1141 tgcgcataca cacacgcgcg cgcgcgcgca cgcgacacac acaggaccca gtgggacaga
1201 tactttatca ctgctgctgt tcagcatgga gggagcttct ttccagtgct ttgtctctcc
1261 gtccactggg cctggtgggt gggtgctcct cagccctctg cttacccacc tctctcttct
1321 cctttagggt tgggcccctc gatgccctgg cctgctgccc actgtgtgac tgtgcctgtg
1381 cctgccagct cccagactgc cagagcctca actgcctctg tttcgagatc aagctcagat
1441 gaaagatggg gctggggacg ttgttctttg gggagtggcc agtccccagg gccccctcta
1501 tgatcctcag gacatcatta tactggagct atggatggca ggcccagcct aattacctgg
1561 gttccttgag ttctctgaaa ggcaggattc tgagagccct tggaccgctg aaaagggcct
1621 gatgctctgg ccagtgcccc tgcctttctt cctctccctt ccctgataaa ctattgtatg
1681 tgaggtagga tcgagacatt gctcacccag gcaacagtgt gggaggtttc tgccaacctg
1741 gactatcagg ataaagggat ggccagccac accctgcctt tagactcctg gttattttaa
1801 gaggtgagta tcctgcctga ctctgctctc ctttggaaaa aaaaaaaaag ttcaaccacc
1861 agcaggcacc agagtcaagg gaggagggaa ccagaggagg gcagtgggag gcaatatcta
1921 gatgttttcc cttcttgttc tgccttaaca gatcctggac ctgagactga tttcttgact
1981 aatttcactg tatttccaag gaagaggttc ctctaaagac cggtgagtga gcagtggcac
2041 ctcctcctct caaggcaaac caaagctgcc tcttcttcac cccccacgca gggatgaatg
2101 tcaggagcct caggtttccc taaatatagg tcccggccgc gggattcgtg gtggggaaag
2161 ggcaggggtt accgagaagg tctgggacac tggtgcgggg gtgtgtaggg gaggggtggg
2221 gagtaggagc tgccttaaaa cccagccctg gactgccggg ctcactctct gctgaccggg
2281 ctctgcggct tctgtcactg cgccacaggt gggccgctat ccggattgca ggatgggaat
2341 gggggttgcg gattgggacc tgaggaaact gactgctctg agagttacag ggtgacaaga
2401 gagctccgag acggattttt ttattttgga gaaggaaatc aggttcggga aagacctgtc
2461 tggcttgggc cagtccttgt cggtcatttc ctcaaactgg gtgtgtttag ctcgcgggtg
2521 gtgcctcccg ccaatctgct aggcaacgcc aggcctggat acgccactca gttccgatgt
2581 ggccggcaca ctagttctgg gaggttttgc ctgcgtacca tgtcactcgc cgtgctctgg
2641 ccagggagag atggaatgng ccctgcattt tagtcaagcg acgaagcagg caggcaggga
2701 ggctccgaag ctctgcgttc ttagcagtga cgtcaggctg caactacaca gccggaagcc
2761 tgggtcttgg aggagaggcc agccaccatc tcactctgac cccctcccta ctcttcgcca
2821 acccacattc cggctgagtc acatgttccg cgcgcgccag gcaggggttg gggggggggg
2881 tgttgggggg ggggggtggt gacctgcggg atgtggctcg agtcacgtcc tagcggggcg
2941 gaggagggat cgtgttctag ccgcttgtct cctccccagt gccgcctcct atcggagcat
3001 cttggggcgg tctgcgcaca gtgcccacct tcaattgacg gttcccgtcc ctgcaaggga
3061 aaaaacctgc agagggcgga gcggcgcctt taaatgtccg gggccccgcc tccggtcccc
3121 cccaacccag ctgaataggc tgggttctct tggaacgcgc agcagaacca ggttctggtg
3181 accctagccg ttcgctcctt agtcctttcg cctacccacc ggcgtaccag gcagacccac
3241 cccgtcctgt gccaggtgag cgccatttac acgtgctcgg ggaagggtct atggggttag
3301 gatcttgggc cggtggcggg cagtgcagag ccgtcttccc cacggcccct cacttctcct
3361 ttttctaccc ccacgcttgc ccccagcccn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
3781 nnnnnnnnnc tggttctctc ttaactctcg cctttgggtt gctatgtggc tttgagcaca
3841 gatcatttct ttcttgggct ctttcagatg agggtattag gctcctgccc tattcgtgat
3901 ccttaaattc taaaatatcc cggttcaatt ttgtttctag gcaaggtgac ccatggcaac
3961 gcgcaggcca gatgggtcag cttcaacatg accgctgtcc tggctctggc ttcttcttcc
4021 ccagttggcc agtgagcgaa cccactctga gctgggcaac acccagcaac agacagagtt
4081 aggaaaggta caggaagagg caggtctagt atagggaagt cgggagtagg ggagagctct
4141 gggacaggaa gtatcccagg accctcaggg agtggggcag gggaggtggg ggctagtgcc
4201 ctggcctcca ggaagctttg taccggggag accatgggat ggtccaacta agcgctggtc
4261 tctgcctccc tcacccagga aagcaactgc caccggcacc atgccccacc catacccagc
4321 actgaccccg gagcagaaga aggagctgtc tgacatcgct caccgcattg tggctccggg
4381 caagggcatc ctggctgcag atgagtccac cggtgcggta caggagaaga aagggaggag
4441 gacccaggtt ggagctagca ggctgatccc ttatctccat catgactttt aggaagcatt
4501 gccaagcgcc tgcagtccat tggcaccgag aacaccgagg agaacaggcg cttctaccgc
4561 cagctgctgc tgactgcaga cgaccgtgtg aatccctgca ttgggggggt gatcctcttc
4621 cacgagacac tgtaccagaa ggcagatgat ggacgtccct tcccccaagt tatcaagtcc
4681 aagggtggtg ttgtgggcat taaggtaaga gggcagactc tggggggggg gtaagattag
4741 aggaggatct cggagaaagg gattaatagg tagggagggg gtaatatggc tagcaggcct
4801 agagactcag gtggatgtat cagcataatt ttttttcagt gtttggggtg aacttaggtc
4861 cttgtgcatg tcggcaagcg cgctgttgcc aacttaatgg ttccctgtga tacaagaagg
4921 tgatttcatg gtgaagaagt gaaaaggttt tctcagtgtg cagtagcacc aggtccctct
4981 agtccagtta acattctctc aaatatacac atcttttctc ataaatatgt gcaagccatg
5041 agaggctaca gtgaaaggtg aagtttgggc ctgggtagag gagacagggg ccataaagct
5101 gactgctggt ctcctccctg gcaggtagat aagggtgtgg tgcccctggc aggaaccaat
5161 ggcgagacaa ctacccaggg taagaatgat ctgcctgcct ccttcccttc tccaccagct
5221 catcagagtt ccagagtgag tctgatcaaa agccttctct ttattcttcc ccttcagggc
5281 tggatgggct gtctgaacgc tgtgcccagt ataagaagga tggagccgac tttgccaagt
5341 ggcgctgtgt gctaaagatt ggggaacata ctccctcggc cctggccatc atggaaaatg
5401 ccaatgttct ggcccgttat gccagcatct gccagcaggt gggattggac tacttcctaa
5461 cacattgatg cagcgcgggc tagctttctg tctatctgcc aggatatctg cctcctcaga
5521 gcagctgctc tcaatacccg ctgtggccag gtcttgagtg gaggtctgca atgtagaggt
5581 ggcaacaggt gtacaggcag attgatagga ttgcttgtcc cctgtaaact gctgaggcct
5641 ttgaagcctg ggtctctgtc atcaagttaa tggtgaggag gctcctagtc aggaggcctt
5701 gcctcattac cctgtccctc ccacagaatg gcattgtacc cattgtggag cctgaaattc
5761 tccctgatgg ggaccatgac ttgaagcgct gccagtatgt tactgagaag gtagtgccat
5821 ctgctgtaga tagtgtgtgc tgcgcgtagt atcgtttcac ttctcgtctg cnnnnnnnnn
5881 nnnnnnnnnn nccctgctgt cttccaggtc ctggcggctg tctacaaggc tctgagcgac
5941 caccatgtct atctggaagg cacattgctg aagcccaaca tggtcacccc tggccatgct
6001 tgcacccaga aattttccaa tgaggagatt gccatggcaa cggtcacagc acttcgtcgc
6061 acagtgcccc ctgctgtcac tggtgaggcc actcctcatc ttggtggtga ggtggatgca
6121 ccatcacatt tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
6181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
6241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
6301 nnngccatgg gccttgactt tctcctatgg tcgagccctg caggcctctg ctctaaaggc
6361 ctggggtggg aagaaggaga acctgaaggc agcccaggag gagtacatca agcgcgccct
6421 ggtaaggcag gcaggcaggc gtggaagtgt gaacaggtgc ctgggcgggg tggggaggga
6481 ctcaagaaga gaattcctct gattcctctt ccttttaggc caacagcctc gcttgtcaag
6541 gaaagtatac cccaagtggc cagtctggag ccgcagccag tgaatctctc ttcatctcta
6601 accatgccta ctaaccagag ctgaactaag gctgctccat caacactcca ggcccctgcc
6661 tacccacttg ctattgaaga ggggtcttca ggctctttcc catcactctt gctgccctcg
6721 tgtgcggtgt tgtctgtgaa tgctaaatct gccatccctt ccagcccact gccaataaac
6781 aactatttaa gggggagtct gttgttcatg tcttgtaggg tataggggag ggctgaggaa
6841 agagctactt gggttcttct tcttggacag taaaaggaag gggttttttg accagagctt
6901 tgagaaaggc atagtattat gggatgttct ttgcctacat ctaattgaag gtaactttta
6961 cactaattaa tattcagttt aagccaacca agggcttatg aatacttggc aaggattgta
7021 tcagggctaa cacatttatg cgttttgggg actatggagc tttggagacg agatctctct
7081 gcagtgacat aggtatacag ctcactgcag aactcttggg ttccaggttg agaatggagc
7141 ctcagagctg ctgatgttcc ctggtgatag aataagaagc acatcaaacc atgggccact
7201 gtatcttgcc acattatatt gagtgtagtc ggtgtgctag tgcacacttt aatccagcac
7261 tcaggaggca gaggcaggca ggaggcaact ggaactcaca aagtgagttc caggacagcc
7321 agggctatac agagaaaccc tgtcttgaaa aaaaaaaatt ctggcctaaa tgaatggata
7381 cagtgtatct gcctttggag gccaaaaggc gtgtatcaag tgctagcttc tggcaagata
7441 agaaacctta aggagtaggg cttcgactat actcagtagc agagtcttgc atggtactca
7501 tggttgtgag cacatgtggt gctaactgct gagtctctct cagtccatca tactctagta
7561 tatagtcaga gactctagat actgacgact agactagact cgtcgtctnn nnnnnnnnnn
7621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
7681 nnnnnnnnnn nnnnnnnnnn nnnnnnnntt ccttcccaag catctttttc tttgacactt
7741 tcgttttcag tgatctgcgt agaattgtct tactaggagt atcaaagcat agtctccact
7801 gtcctaatat tcccatgtat tggccaatag tcaaagctat gcgcaggctg tggatagagc
7861 ccagtggctg agtacccaaa gctctggttc cttccccagt gctgcaaggg aaaactcaaa
7921 tccctatgct tccccaaact tcagcctccc attttactgc tcatcacgta cttgtagcct
7981 tgctctctag aattctgtag cccacactgg ccttgaactc tcaagatctg ctttccaagt
8041 actgggatga aaggcatgtg ctattctcct agcttctatg aggcgatcct ttttatttta
8101 tatacattgg tattaactga atgtgtgtat gtgtgtagtg tgatccggta cgagctcgag
8161 cgtatagtga gtcgatacat catgcgcgct
//