Drosophila melanogaster
LOCUS DROPFK 7101 bp DNA INV 23-FEB-1995
DEFINITION Drosophila melanogaster phosphofructokinase (pfk) gene, complete cds.
ACCESSION L27653
VERSION L27653.1 GI:514918
KEYWORDS phosphofructokinase.
SOURCE Drosophila melanogaster (strain Oregon) adult DNA.
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila.
REFERENCE 1 (bases 1 to 7101)
AUTHORS Currie,P.D. and Sullivan,D.T.
TITLE Structure and expression of the gene encoding phosphofructokinase (PFK) in Drosophila melanogaster
JOURNAL J. Biol. Chem. 269 (40), 24679-24687 (1994)
MEDLINE 95014229
COMMENT On Jul 23, 1994 this sequence version replaced gi:471780.
FEATURES Location/Qualifiers
source 1..7101
/organism="Drosophila melanogaster"
/strain="Oregon"
/db_xref="taxon:7227"
/dev_stage="adult"
TATA_signal 698..704
exon 719..1048
/number=1
5'UTR 719..901
gene join(902..1048,2070..2414,2472..2635,3008..3110,
4291..4476,4663..5102,5160..5999,6079..6217)
/gene="pfk"
CDS join(902..1048,2070..2414,2472..2635,3008..3110,
4291..4476,4663..5102,5160..5999,6079..6217)
/gene="pfk"
/codon_start=1
/product="phosphofructokinase"
/protein_id="AAA62385.1"
/db_xref="GI:514919"
/translation="MNSEINQRFLARGSQKDKGLAVFTSGGDSQGMNAAVRACVRMAIYL
GCKVYFIREGYQGMVDGGDCIRKSNWASVSSIIPFVGWHHPLLRPLPDFRERQGRL
KAANNLIQRGITNLVVIGGDGSLTGANLLPQEWSSLLDELVKNKTITTEQQEKFNV
LHMLGLVGSIDNDFCGTDMTIGTDTALHRIIEQSKAKVQSPVQPNSHQRTFIMEGQ
VSHCGYLALVGGLACEAIHIHPNAPGRLGQTGSALSWTQRSAGQRLNIVIVAEGAM
DREGHPITAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRFLACRMGAEPLWP
LMEATKDSVPVVISLDGNQAVRVPLMECVERTQAGKAMAEKRWADAVNVRGRSF
ERNLETYKMLTRLKPPKENFDADGKGIEGYRLAVMHIGAPACGMNAAVRSFVRNA
IYRGDVVYGINDGVEGLIARNVRELGWSDVSGWVGQGGAYLGSKRTLPEGKFKEIA
ARLKEFKIQGLLIIGGFESYHAAGQIADQRTTTHSFCIPIVVIPSTISNNVPGTEFSLGC
DTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLPPLAGLAGGADAAYIYEEK
FSIKELQQDVYHMPPRWPRRLPRSNPANEKASENYSTDFIYRLYSEEGKGLFTCRM
NILGHMQQGGSPTPFDRNMGTKMAAKCVDCWPPRSRRTSTANGVVNCKSPDTAT
LLGIVSRQYRFSPLVDLIAETNFDQRIPKKQWWLRLRPLLRILAKHDSAYEEEGMYIT
VEEECDTDAVA"
intron 1049..2069
/gene="pfk"
/number=1
exon 2070..2414
/gene="pfk"
/number=2
intron 2415..2471
/gene="pfk"
/number=2
exon 2472..2635
/gene="pfk"
/number=3
intron 2636..3007
/gene="pfk"
/number=3
exon 3008..3110
/gene="pfk"
/number=4
intron 3111..4290
/gene="pfk"
/number=4
exon 4291..4476
/gene="pfk"
/number=5
intron 4477..4662
/gene="pfk"
/number=5
exon 4663..5102
/gene="pfk"
/number=6
intron 5103..5159
/gene="pfk"
/number=6
exon 5160..5999
/gene="pfk"
/number=7
intron 6000..6078
/gene="pfk"
/number=7
exon 6079..>6217
/gene="pfk"
/number=8
polyA_signal 6452..6457
polyA_signal 6545..6550
polyA_signal 6773..6778
BASE COUNT 1809 a 1651 c 1623 g 2018 t
ORIGIN
1 agcttataga ttcagcttgt accatgccag gaataacatg aggattaacg cgcacgttca
61 tttctgggtc tgtcaccggc gcggctaaat ttacaacttg ctgccagaat gtgccgccaa
121 gaaccgcggt ttgtgccgga cgcacaacgc cttaacccaa ggcaaccaag ctgcagctgc
181 ctcctccaag caccaccgga gtgcccgcct tagcagccag cagtttccgc cgctttgtga
241 acttaccacg cccagcaatg tgccggtttc tttgacagga gaaagaatat cggtcatcgt
301 aggccagcca tatccagcaa tgcaggtttc cagtcacggg tggttagatc aagaagtccc
361 gtggtgccag cgttagaggg atcaacagct gaacgattgt gggtcgaacg taaacaaatt
421 ggttaaacgc tattttccgc tcgttgctag tcgcgaaagt cgttcataac agacagaatc
481 ctcagatttt cgacctaaat caaaccaagt tagggcaatc gcgttggagc gaactcttgg
541 gcggatttag ccatccgaag tttgcattgc atcagtacgc acttacagaa agcccgtggc
601 tgtgtgctgt gtccgtgtgt gttgtgtatg cgtctctggc ctgaaggtca ccttgaagct
661 caaagcaaag cgaactgtga ataccgcctg cgagcggtat atattgctag taactgaaaa
721 gccacggcaa ggagacgtag tagtagtatt tatagcccac ttgatataac ccagctccag
781 cggcgctgct cgcatagttg caaaactccc taccgagtac aatagtggtt catagtgtgt
841 gctttgtgcg atatccgtta cgaccccagt ttgatttaca tatagtgcaa aagattgaaa
901 aatgaattcc gagattaatc aacgattcct ggcccgcggc tcgcagaagg acaaaggact
961 ggcggtcttc accagcggcg gggattccca gggcatgaat gccgccgtgc gagcctgtgt
1021 ccgtatggcc atctatttgg gctgcaaggt gagttggtga cctctgtcaa gtacttccgc
1081 ccacgcagat cgcgtccggt gaccccgatc ccaggcacag gcaacaaacc catagtgaac
1141 ccagaaattt cgtgaaacac ctggtaattt gcttatcagc agccgttaaa ccacgattat
1201 tgggccgcaa agccagttag ataatctcca atcggtgcga aaagaaattc aagaatatat
1261 gtgtacatgc acattgacat tgggtttatt ttcgggtcct cacatgcgat tttcgatttt
1321 cggctaattt gtttcgtttt tttgttgtcg ctcttggttt ctattcggtt tatttaaatg
1381 agttctttaa tttgttaggg aacttcttgc ccggccgttg gctccctcga aatatcgaaa
1441 atgtgtcaat taacgtagcc aatttaaatt gataaactat tcatttgatt caatttctgg
1501 ggcataaagt aaagtattgc tgccttgcat gaccagcgct tgaatatggt tcaataaatt
1561 gacaaattaa taaatatatc atggtatgct aaacaaatgg ttcctaatca gttcaataat
1621 ctaacctttg tttttaatct actagtgcct tggcatcatt attgtttatg ttattttttc
1681 acttttcaaa ttaagagcgt tataaaattt gaattccctt ggttatctga gttgcttaaa
1741 aagtatcgat ttaacatcga ttacattgta attacctgta acggtatttt gaatatgcaa
1801 atgttttgtt gtttaaaact taaacttatc agtaaaagtt gagaaaagta tatgagataa
1861 gtcatatcat attaatttct attgactgtt ctttactgac ttcctattaa atattacgac
1921 tttggcagag tgaaatgaaa ttaaataatt tatactcgaa ttcggtgatt catttttaat
1981 tgtgctaatg atgtcatgtg ccatgaagat accaaactct attctgtttt acaccatatc
2041 tacaattgat tcgtgtttac ttcggcaagg tctacttcat tcgtgaaggc taccagggca
2101 tggtggatgg tggcgactgc atcaggaagt ccaactgggc ctcagtctca tccattattc
2161 cattcgttgg ttggcaccat ccattgctcc gccctttgcc agacttccgt gagcgtcagg
2221 gtcgcttgaa agccgctaac aacctgattc agcgaggaat caccaatctg gtggtcattg
2281 gaggcgatgg ctccctcacg ggcgccaatc tgttgcctca ggagtggtcc agcctgttgg
2341 acgagctggt caagaacaag accattacca ccgagcagca ggaaaagttc aatgtcctgc
2401 acatgcttgg attggtatgc tacacagagt attccttgga tatattttct tatggatgaa
2461 tctttttgta ggttggctcc atcgacaacg atttctgtgg cactgacatg accatcggca
2521 cggacacggc actgcatcgc atcatcgagc aatcgaaggc taaggtccaa tctccagtac
2581 agcctaactc ccatcagcgc accttcatca tggaaggtca ggtgtctcat tgcgggtaag
2641 ttgatctctg agcggatatt gcgaggaaaa gttggatgcc tctgtattag cctaagtgtc
2701 agtgattaaa ttgggatttt agctaatgcc tggaacgact atctctagct atctttcggt
2761 ggtagctggc attatctccg aaggcaagac tacgtctttc tgcccgagtc tcctccgcag
2821 ccgattggcc cgatcgactt gtccttaaat tggaacaggc aagcccaaaa cggaaatctg
2881 ttgaatgtcg tcgactcatt tcgcacattt ctgtttctat ggccgcagta ctatgtcgat
2941 cgatccccat atcctccaaa atcccatccc ccttttgact aatattttgt aatatatatt
3001 tttgcagcta tttagctctt gtgggtggac tggcgtgcga ggcgattcat attcatccga
3061 atgcgccagg tcgattaggc cagacaggct ctgctctcag ctggacccag gtcaggaaga
3121 tgagctccat ttccattcca tcaagtcact ggagaagtcc gaaaggcatc ggaaatatgt
3181 tctcgagaga cttggtatag gatttaggat attcttatta atatagccag ttagctgtcg
3241 aagataatat tcctgtttga gatagagttg tatacttcag tgcagttgtc gttgcttgat
3301 gcttaagtag tacacctgta cacaattttt tgaaagacac attttaagag cgacacttgc
3361 catacaaagc ttggttctta tttctgctta ctgcacacga atgtatcttt aaacacaaac
3421 cggagatacg gaatgaatta cgcacagttt ttgatctgta ccagcataca aaatcatatg
3481 taactaactt aagtttaccc agatactcca atcccggata atatctcccg acattgtgaa
3541 ccatctttat tttgtaccta actcttgttt ttagttacta gccatatcgg cagccaatag
3601 gccacagagg ctgatttatg ttcatacccg agagccggtg tcagtcaatt ggaaggacag
3661 atctgtgtca agctccacca ggtcaggtcc agagtccttc gctatccaat taatttctag
3721 ctactctttt gtcaaatttt tgaatttcta aattttattc tgcattgttt ttggactatt
3781 cgatgtgccg aaatttccat ggtggcgata aacagcttta acagctattt gatttacttg
3841 tttgggtttt cggtctctgt ttttgagtac cactatgatc tcactgagtt cccttactaa
3901 cttttccaaa tccactaacg tccatcctcg ttaatcgatc gtaaatcttc atcaatgttt
3961 ctattcatcg acttgactga tcggctaagg atcggctcaa gtcaacgtta atctaatcat
4021 gaagcccgca ttatgatcga actgaatcat gaatatcata gaataacgtg agtactttag
4081 aacgcatgca ctcatcgctt gctgatacac atttggtgac actattcaac attgtaagca
4141 aagcatatgt aaactacatt attgtatgat gatgtctact catcatgccc tcttcataat
4201 tcgtttgtgc ttttgtagtt tctgtatcat ccacgattag tatcttacat atatgcttaa
4261 atgaatccct tcaccattga ccaacaggag cgatctgctg gccagcgtct gaacatcgtg
4321 attgtggccg agggagccat ggatcgcgag ggtcatccca tcacagccga ggatgtaaag
4381 aaggtgatcg acgagcgtct gaagcacgat gcccgcatca ctgtcttggg tcacgtgcag
4441 cgcggtggca atcccagtgc cttcgatcgt tttttggtaa gtatttatac gaagatgacc
4501 tcaataactg tatttttagt aatttacaat gctagctagt tttagattgt atcttttaaa
4561 ggttaatatt aaaacactaa agttaccaaa ataaggatat acttattaag atatgattca
4621 atctattttt gacttgagag ttaatgcttc taccccgcat aggcttgccg catgggagct
4681 gagccacttt ggcccttgat ggaggccacc aaggactcgg tgccagtggt catctctctg
4741 gacggcaacc aggcggttcg cgtgccgctg atggagtgcg tggagcgcac ccaggctggc
4801 aaggccatgg cggagaaacg ctgggcggat gccgtcaacg tgcgcggacg ctccttcgag
4861 cggaatctgg agacctacaa gatgctgacg cgcttgaagc cgcccaagga gaacttcgac
4921 gccgatggca agggaatcga aggataccgc ctagctgtga tgcatattgg tgctccggct
4981 tgcggtatga atgccgctgt gcgcagcttc gtgcgcaatg ccatctaccg cggtgatgtg
5041 gtttatggaa tcaacgacgg tgtcgagggt ctgattgcgc gaaatgtccg cgagctgggc
5101 tggtaagtaa tccgacaagg gatcactcta aatcgtgtct taatgcaatt caatttcagg
5161 tcggatgtct caggatgggt tggtcagggt ggcgcctact tgggatccaa acgcacactg
5221 cctgagggca agttcaagga gatcgccgct cgtctcaagg agtttaagat ccagggtctc
5281 ctgatcattg gtggctttga gagttaccat gccgccggac agatcgccga tcagcggaca
5341 actacccaca gcttctgcat ccccattgtg gttattccat cgacgatttc gaacaatgtg
5401 cccggcacag aattttctct gggatgcgac accggtttaa atgagattac ggagatttgc
5461 gaccgtatcc gtcagtcggc acagggaacc aagcgccgag tgttcgtcat tgagacgatg
5521 ggtggctact gtggctattt gccaccgttg gccggtttgg ccggcggagc tgatgccgcc
5581 tacatctacg aggagaagtt ctccatcaag gagctgcagc aggatgtcta ccacatgcct
5641 ccaagatggc cgaggcgtct cccgcggtct aatcctgcga acgagaaggc tagcgagaac
5701 tacagcacgg acttcattta ccgcctgtac tcggaggagg gcaagggcct cttcacctgc
5761 cgtatgaaca tcctgggtca catgcagcag ggcggctcac ccactccctt cgaccgcaac
5821 atgggcacca aaatggccgc caagtgtgtc gactgctggc cgcccagatc aaggcgaaca
5881 tcgacggcca acggtgtggt caactgcaag tccccggaca ccgccacgct gctgggaatc
5941 gtgtcgcggc agtaccgctt ctcaccgctg gtcgacctca ttgcagagac gaacttcgag
6001 taagtttaac ccgatggtca ccacaaaggg gactatgaat tccctttaag ctcttggcat
6061 aacccactcc tcttccagtc aacgcatccc gaagaagcag tggtggctgc gcctgcgtcc
6121 cctgctgcgc atcctggcca agcacgattc cgcctacgag gaggagggta tgtacatcac
6181 cgtcgaggag gagtgtgaca ctgacgccgt cgcctaagcg gactcggatc cggactctga
6241 tccccacttc cgcttatcac caccatcgct gcatgcaagc atcaatgtcc acctatccgc
6301 accctcgaat cagtctctgt gttcgctttt taagttgttt tggcaccgca tccgatccgt
6361 tttatggttt ttaccaagat cagacgaaga ggcccatgac agcagcacat acgaaagtat
6421 ttcataatct acagacgcat aaaaaagcac aaatacataa cttatttata ttgctcgcca
6481 gtcgattctt tcttatgatt tttccaaata tcgtgtattc ttgaaatttg aatctcgaat
6541 actgaataac gttaatagtt cattctacat tgcagccgtt ccgaagagtc tggcgaccta
6601 ttagcggaaa acgtttcgta tattatcgta attgttggtt cttcagccca actaaattaa
6661 atgttaaagt atttagacaa tttacccagt caaaggaaca aattctatct gcaaactgtt
6721 tttcgagtat tgttatcgaa cgaagcaatg atctatttgt aacgacgtgc taaatacata
6781 tcaaacacct gttggcacaa tttatcgtcg tttgttttct aattgttcag taggtatgtg
6841 ggaattgagc ttgaatttca cttttggtta agaaaacatt tatttttgaa atggcttgct
6901 gggcgcgatt ggaacagcaa tgtttcagtg gaatcagcct ataatacgat gtttctgcag
6961 caacttcact gcttgcaagc tatcggctca atcgattgtg gtgccatcga tgcgcttcca
7021 gcctagacac ttgacttttt gcacggatgt gtatgtagtt tattgtgctc gaaactgcgt
7081 aagtgatgtc agcgtgactg a