Rattus norvegicus
LOCUS NM_013190 2740 bp mRNA ROD 12-FEB-2000
DEFINITION Rattus norvegicus Phosphofructokinase, liver, B-type (Pfkl), mRNA.
ACCESSION NM_013190
VERSION NM_013190.1 GI:6981351
KEYWORDS .
SOURCE Norway rat.
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 2740)
AUTHORS Hotta,K., Nakajima,H., Yamasaki,T., Hamaguchi,T., Kuwajima,M., Noguchi,T., Tanaka,T., Kono,N. and Tarui,S.
TITLE Rat-liver-type phosphofructokinase mRNA. Structure, tissue distribution and regulation
JOURNAL Eur. J. Biochem. 202 (2), 293-298 (1991)
MEDLINE 92104147
COMMENT REFSEQ: This reference sequence was derived from X58865.1.
PROVISIONAL RefSeq: This is a provisional reference sequence record that has not yet been subject to human review. The final curated reference sequence record may be somewhat different from this one.
FEATURES Location/Qualifiers
source 1..2740
/organism="Rattus norvegicus"
/strain="Sprague Dawley"
/db_xref="taxon:10116"
/chromosome="20"
/map="20"
/clone="lambda-PFKL1-PFKL8"
/tissue_type="liver"
/clone_lib="lambda-gt10"
gene 1..2740
/gene="Pfkl"
/db_xref="LocusID:25741"
/db_xref="RATMAP:44478"
RBS 62..70
CDS 67..2409
/gene="Pfkl"
/EC_number="2.7.1.11"
/codon_start=1
/product="phosphofructokinase, liver, B-type"
/protein_id="NP_037322.1"
/db_xref="GI:6981352"
/translation="MATVDLEKLRMSGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYV
GAKVFLIYEGYEGLVEGGENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAA
YNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLSIAG
LVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALV
SALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISS
SYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRVLSSKMGMEAVMALLEATPDTPAC
VVSLSGNQSVRLPLMECVQVTKDVQKAMDEKRFDEAIQLRGRSFENNWKIYKLLAHQK
VSKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYVVHDGFEGLAKGQVQEV
GWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENLRTYNIHALLVIGGFEAYEGVLQLV
EARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRV
FIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRGLV
LRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKA
MLWMSEKLRDVYRKGRVFANAPDSACVIGLRKKVVAFSSVTELKKETDFEHRMPREQW
WLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF"
polyA_signal 2722..2727
polyA_site 2740
BASE COUNT 579 a 762 c 864 g 535 t
ORIGIN
1 ggcgacagcc gcgcggaacg cagagcggcg ggagaggagc tcgggctcct ggtctctgct
61 gccgtcatgg ctaccgtgga cctggagaag ttgcggatgt cgggggctgg caaggccatc
121 ggagtgctga caagcggcgg tgacgcgcaa ggtatgaatg ctgctgtcag ggctgtgact
181 cgtatgggca tatatgtggg ggccaaagtc ttcctcatct acgagggcta cgagggcctc
241 gtggaaggag gcgagaacat caagccagcc aactggctca gtgtctccaa catcatccag
301 ctgggcggca ccatcattgg cagtgcccgc tgtaaggcct tcactacgag ggaagggcgc
361 ctggcagcgg cctacaatct gctccaacac ggcatcacca acctgtgtgt catcggtggg
421 gatggcagcc tcacgggggc caacatcttc cgcaacgagt ggggcagctt gctggaggaa
481 ctggtgaagg aaggcaagat ctcagagtcc acagctcaga actacgcaca cttgagcatc
541 gccggtctgg tgggctccat cgacaacgac ttctgcggca ccgacatgac catcggcacg
601 gactcggccc tgcaccggat catggaggtc atcgacgcca tcaccaccac tgcccagagc
661 caccagagga cctttgtgtt ggaggtgatg ggacggcact gcgggtacct ggcgctggtg
721 tctgcgctgg cctccggggc tgattggctg ttcatccctg aagcgccccc ggaggatggc
781 tgggagaact tcatgtgtga gaggctgggg gagactcgga gccgggggtc tcgactgaac
841 atcatcatca tcgcggaggg tgccatcgac cggcatggaa agcctatctc atccagctac
901 gtgaaagacc tggtggttca gaggctgggc ttcgatacac gagtgaccgt gctgggccac
961 gtacagcgag gagggacacc ctcggccttt gaccgagtcc tgagtagcaa gatgggtatg
1021 gaggccgtga tggcgctgct ggaggccacg ccggacacgc cggcctgcgt ggtcagcctc
1081 tccgggaatc agtctgtgcg gctgcctctc atggagtgtg tgcaagtgac gaaggatgtg
1141 cagaaggcca tggatgagaa gaggtttgac gaggccatcc agctccgtgg caggagcttc
1201 gagaacaact ggaaaattta caagctcctc gcccaccaga aggtgtctaa ggagaagtcc
1261 aacttctccc tggccatcct gaatgtggga gctccagcgg ccggcatgaa cgcagccgtg
1321 cgctccgcgg tacgcactgg catctccgag ggacacacag tgtacgttgt gcatgatggc
1381 tttgagggcc tggccaaggg tcaggtgcaa gaagtgggct ggcatgatgt ggcaggttgg
1441 ctaggacgtg gtggctcaat gctggggacc aagaggaccc tgcccaagcc ccacctggag
1501 gccattgtag aaaatctccg tacctacaac attcatgccc tgttggtgat cggtggcttt
1561 gaggcctacg agggtgtgct gcagctggtg gaggctaggg ggcgctacga ggaactctgt
1621 atcgtcatgt gcgtcatccc agccaccatc agcaacaatg tccctggcac tgacttcagc
1681 ctgggctcgg acacggccgt caacgctgca atggagagtt gtgaccgcat caaacaatcg
1741 gcctcgggga caaagcggcg tgtgttcatt gtagagacca tggggggcta ctgtggctac
1801 ctggccactg tgacaggcat tgctgtgggc gccgatgccg cctacgtctt tgaggaccct
1861 ttcaacatcc acgacttgaa ggccaatgtg gagcatatga cagagaagat gaagacagac
1921 atccagaggg gcctggtgct ccggaacgag aagtgtcacg aacactacac cacggaattc
1981 ctatacaacc tatactcctc ggaaggcaga ggtgtgttcg actgcaggac caacgtgctg
2041 ggccacctgc agcagggtgg cgctccaacc cccttcgacc ggaactatgg gaccaaactg
2101 ggggtgaagg ccatgttgtg gatgtcggag aagctgcgtg atgtctaccg caaagggcgg
2161 gtgtttgcca atgctccgga ctcagcctgt gtgatcggcc tgaggaagaa ggtggtggcc
2221 ttcagttcgg tcacagaact caagaaagag acagattttg agcaccgtat gccgcgggag
2281 cagtggtggc tgaatctgcg gctgatgctg aagatgttgg cacactaccg catcagcatg
2341 gccgactacg tgtctgggga gctggagcac gtcacacgcc gcaccttgag catagacaag
2401 ggtttctgag cttaccgatc accctcgttc ctgctctccc ggactctctc tccctcccag
2461 tgctagccac agatcccagc actaagggga actcacatgg aactcggagc ctgtggttgg
2521 ttgaaggatt tgggggtcta ctgtgctgct ctgggactcc tcccttagcc acccccaccc
2581 ccccaccccc tcagaacaga gcacctgtgg ggcccttaca ttccagttct ggctgggcag
2641 acccacatca ccactccctc actggtcagc tggctgcctc accacacggc cgaaaagagc
2701 ctcatggttt ttttttttag aaataaagtc acctgtttag