LOCUS MUSPGSF 3986 bp mRNA ROD 27-APR-1993
DEFINITION Mus musculus prostaglandin synthase mRNA, complete cds.
ACCESSION M64291
VERSION M64291.1 GI:200336
KEYWORDS prostaglandin synthase.
SOURCE Mus musculus (strain Swiss) cDNA to mRNA.
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus.
REFERENCE 1 (bases 1 to 3986)
AUTHORS Kujubu,D.A., Fletcher,B.S., Varnum,B.C., Lim,R.W. and
Herschman,H.R.
TITLE TIS10, a phorbol ester tumor promoter-inducible mRNA from swiss 3T3
cells, encodes a novel prostaglandin synthase/cyclooxygenase
homologus
JOURNAL J. Biol. Chem. 266, 12866-12872 (1991)
MEDLINE 91302297
FEATURES Location/Qualifiers
source 1..3986
/organism="Mus musculus"
/strain="Swiss"
/db_xref="taxon:10090"
/cell_line="Swiss 3T3"
CDS 125..1939
/codon_start=1
/product="prostaglandin synthase"
/protein_id="AAA39924.1"
/db_xref="GI:200337"
/translation="MLFRAVLLCAALGLSQAANPCCSNPCQNRGECMSTGFDQYKCDC
TRTGFYGENCTTPEFLTRIKLLLKPTPNTVHYILTHFKGVWNIVNNIPFLRSLTMKYV
LTSRSYLIDSPPTYNVHYGYKSWEAFSNLSYYTRALPPVADDCPTPMGVKGNKELPDS
KEVLEKVLLRREFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPGFTRGLGHGVDLNH
IYGETLDRQHKLRLFKDGKLKYQVIGGEVYPPTVKDTQVEMIYPPHIPENLQFAVGQE
VFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDY
VQHLSGYHFKLKFDPELLFNQQFQYQNRIASEFNTLYHWHPLLPDTFNIEDQEYSFKQ
FLYNNSILLEHGLTQFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKYQSLN
EYRKRFSLKPYTSFEELTGEKEMAAELKALYSDIDVMELYPALLVEKPRPDAIFGETM
VELGAPFSLKGLMGNPICSPQYWKPSTFGGEVGFKIINTASIQSLICNNVKGCPFTSF
NVQDPQPTKTATINASASHSRLDDINPTVLIKRRSTEL"
BASE COUNT 1170 a 853 c 809 g 1154 t
ORIGIN
1 agttgtcaaa ctgcgagcta agagcttcag gagtcagtca ggactctgct cacgaagaat
61 ctcagcactg catcctgcca gctccaccgc caccaccact gccacctccg ctgccacctc
121 tgcgatgctc ttccgagctg tgctgctctg cgctgccctg gggctcagcc aggcagcaaa
181 tccttgctgt tccaatccat gtcaaaaccg tggggaatgt atgagcacag gatttgacca
241 gtataagtgt gactgtaccc ggactggatt ctatggtgaa aactgtacta cacctgaatt
301 tctgacaaga atcaaattac tgctgaagcc caccccaaac acagtgcact acatcctgac
361 ccacttcaag ggagtctgga acattgtgaa caacatcccc ttcctgcgaa gtttaactat
421 gaaatatgtg ctgacatcca gatcatattt gattgacagt ccacctactt acaatgtgca
481 ctatggttac aaaagctggg aagccttctc caacctctcc tactacacca gggcccttcc
541 tccagtagca gatgactgcc caactcccat gggtgtgaag ggaaataagg agcttcctga
601 ttcaaaagaa gtgctggaaa aggttcttct acggagagag ttcatccctg acccccaagg
661 ctcaaatatg atgtttgcat tctttgccca gcacttcacc catcagtttt tcaagacaga
721 tcataagcga ggacctgggt tcacccgagg actgggccat ggagtggact taaatcacat
781 ttatggtgaa actctggaca gacaacataa actgcgcctt ttcaaggatg gaaaattgaa
841 atatcaggtc attggtggag aggtgtatcc ccccacagtc aaagacactc aggtagagat
901 gatctaccct cctcacatcc ctgagaacct gcagtttgct gtggggcagg aagtctttgg
961 tctggtgcct ggtctgatga tgtatgccac catctggctt cgggagcaca acagagtgtg
1021 cgacatactc aagcaggagc atcctgagtg gggtgatgag caactattcc aaaccagcag
1081 actcatactc ataggagaga ctatcaagat agtgatcgaa gactacgtgc aacacctgag
1141 cggttaccac ttcaaactca agtttgaccc agagctcctt ttcaaccagc agttccagta
1201 tcagaaccgc attgcctctg aattcaacac actctatcac tggcaccccc tgctgcccga
1261 caccttcaac attgaagacc aggagtacag cttcaaacag tttctctaca acaactccat
1321 cctcctggaa catggactca ctcagtttgt tgagtcattc accagacaga ttgctggccg
1381 ggttgctggg ggaagaaatg tgccaattgc tgtacaagca gtggcaaagg cctccattga
1441 ccagagcaga gagatgaaat accagtctct caatgagtac cgcaaacgct tctccctgaa
1501 gccgtacaca tcatttgaag aacttacagg agagaaggaa atggctgcag aattgaaagc
1561 cctctacagt gacatcgatg tcatggaact gtaccctgcc ctgctggtgg aaaaacctcg
1621 tccagatgct atctttgggg agaccatggt agagcttgga gcaccattct ccttgaaagg
1681 acttatggga aatcccatct gttctcctca atactggaag ccgagcacct ttggaggcga
1741 agtgggtttt aagatcatca atactgcctc aattcagtct ctcatctgca ataatgtgaa
1801 ggggtgtccc ttcacttctt tcaatgtgca agatccacag cctaccaaaa cagccaccat
1861 caatgcaagt gcctcccact ccagactaga tgacattaac cctacagtac taatcaaaag
1921 gcgttcaact gagctgtaaa agtctactga ccatatttat ttatttatgt gaaggaattt
1981 aatttaatta tttaatattt atactgaatt ttttttcatg taacatcttc cataacagaa
2041 ggcaatgttc ttgaacaatg ttacatttgt gaagattcct ccggtgtttg tcctttaaat
2101 atgtgttacc tgaaactgaa aggaaatcag cattcattcc tctacataag ccagtgagaa
2161 gggaaatgaa ttttgatatc tttatacttg aatttcagat catgaattag cttaacaaga
2221 accaaggaaa aatgtatgaa tatgtgagtg ttgttacaag atgaaaaatg ctgcaggtat
2281 caacactgtt ggttacactg tgtcttcttt acctatgata ggagcatgta atgtggaatt
2341 cgtcttaaat ccttgcatat ctttatctca tcaaacaaag gggtccaagt tcagttttaa
2401 ataagcattt aaggcagata ctgacaacaa tctcattttt ttaaaatgtt gtcttgagac
2461 aaataatttg aaatttctaa attgggacgt ttgaatcact tttgaaagct cttactttct
2521 taagctgtca ggtttgtacc gacatggagt aaacagctat cataaacgta aatctccaaa
2581 actagtagaa attatgtcat gattgatggt taagatacca tgtcagggat tgtcttttct
2641 tagaagtagt gaaagctact tactatgaca atcagacctt ccttgtatgt caaaatgctg
2701 gtgtggaagg tggtggagcc cgtgctgctc tgtcttaact atgagtgtga gctttaaagc
2761 tcgttgatga gtggtagcca gcaaagccta gagcaacaaa agcgttctac aaaggaacta
2821 accaagaaca aagaagggtt cccaattaaa gatcacattc agggttaaac ttccaaagga
2881 gacatcctga tcctggtttt gtgctggcct ggtactcagt aggtttttgc tgtgaggtta
2941 aagacttgcc agggctgaac ttcgaaacag tttttctgtt gcacagtatg atgtaacagt
3001 ccatctctca atgcaatagg tatcagtggc ctcgtgagct tcttcacaat atttgatatg
3061 tcttccagcc cattgaacct ggactgcaga aggccccatg tcatgtgtga gctcagcctg
3121 gatgccagca tttgctgctc ctcttagttc cgtttctcgt ggtcacttta ctacgagaaa
3181 cgctgattgg gttttcgtag ctgtgttacc aggtttttag tatcagaact attctttctt
3241 taacctctat tcatattttc tctacttgaa gttttacatt caggaaaacc tcagcgctca
3301 ggactactat gtacctcccc tttggaggga aaaattcatt tttaggtaaa aggcaaaaat
3361 tttttaaaaa tattttttat ttataattat atggaagggc cctaccaaga tgctagaaat
3421 atagggagtt cctgacaaga aatttccatt cttattctga agaattgctt tcttacttaa
3481 aaacaaagac agtttgtgag tagttctggg caatagggat aaatataaaa caataatgat
3541 gatcattttc tacatctcat tatcagctga ggtactgtat attactgaat ttattgaaga
3601 tagttatgtc ttttagacat tgttgttata aactatgttt aagcctacta caagtgtttc
3661 ttttttgcat tatgttggaa ttgatgtacc ttttttatga ttacctctct gaactatggt
3721 gtgaacaatc aaacaaaatg atgagattaa cgttcatgga taaattctaa gaaaactagt
3781 gtattttttt gaaaagtttg aagttagaac ttaggctgtt ggaatttacg cataaagcag
3841 actgcatagg atccaatatt gactgaccca agcatgttat aaagactgac attttagaca
3901 ttttgaaggc cctgtaagtg tttattaatt agttagaact taattgatta aaaaatatat
3961 ccaaagcact ataggcatta gaattc