LOCUS SHPPGS 2666 bp mRNA MAM 27-APR-1993
DEFINITION Sheep prostaglandin G/H synthase mRNA, complete cds.
ACCESSION J03599
VERSION J03599.1 GI:166035
KEYWORDS prostaglandin synthase.
SOURCE Sheep vesicular gland, cDNA to mRNA, clone PGHS-ov.
ORGANISM Ovis sp.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
Eutheria; Cetartiodactyla; Ruminantia; Pecora; Bovoidea; Bovidae;
Caprinae; Ovis.
REFERENCE 1 (bases 1 to 2666)
AUTHORS DeWitt,D.L. and Smith,W.L.
TITLE Primary structure of prostaglandin G/H synthase from sheep
vesicular gland determined from the complementary DNA sequence
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85, 1412-1416 (1988)
MEDLINE 88144447
COMMENT Draft entry and computer-readable sequence for [1] kindly provided
by D.L.DeWitt, 19-JAN-1988.
FEATURES Location/Qualifiers
source 1..2666
/organism="Ovis sp."
/db_xref="taxon:9939"
mRNA <1..2666
/note="prostaglandin G/H synthase mRNA"
sig_peptide 93..164
/note="prostaglandin G/H synthase signal peptide"
CDS 93..1895
/note="prostaglandin G/H synthase precursor (EC
1.14.99.1)"
/codon_start=1
/protein_id="AAA31576.1"
/db_xref="GI:166036"
/translation="MSRQSISLRFPLLLLLLSPSPVFSADPGAPAPVNPCCYYPCQHQ
GICVRFGLDRYQCDCTRTAIPAPTAPSRRYGPGSGRLCGPAPLSSTFMLTHGRWLWDF
VNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCP
TPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGP
GFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYP
RGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARL
ILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHWHPLMP
DSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVD
VIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLL
LEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATLKK
LVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL"
mat_peptide 165..1892
/note="prostaglandin G/H synthase"
BASE COUNT 541 a 760 c 737 g 628 t
ORIGIN Unreported.
1 gcgggcccga ggggccggag ctcccgggca gagttagaga cgcactccag gagcctgagt
61 cggtctccag cacgcaacgg ccaccctgca ccatgagccg gcagagtatc tcgctccgat
121 tcccgctgct tctcctgctg ctgtcgccat cccccgtctt ctcagcggac cccggggcgc
181 ccgcgccagt gaacccctgc tgttactatc catgccagca ccaggggatc tgtgttcgct
241 tcggccttga ccgctaccaa tgtgactgca cccgcacggc tattccggcc ccaactgcac
301 catcccggag atatggacct ggctccggac gactttgcgg cccagcccct ctttcatcca
361 ctttcatgct gacgcacggg cgctggcttt gggattttgt caatgccacc ttcatccggg
421 acacgctcat gcgtctggta ctcacagtgc gttccaacct tatccccagc cctcccacct
481 acaacatagc gcacgattac atcagctggg agtccttctc caatgtgagc tattatactc
541 gcattctgcc ctccgtgccc cgagactgtc ccacgcccat gggcaccaaa gggaagaagc
601 aattgccaga tgcggagttc ctgagccgtc gcttcctgct caggaggaag ttcatccctg
661 accctcaagg caccaacctc atgtttgcct tctttgccca acacttcacc catcagttct
721 tcaaaacttc cggcaagatg ggtcctggct tcaccaaggc gctgggccac ggggtagacc
781 tcggccacat ttatggagac aatctggaac gtcagtatca gctgcggctc tttaaggatg
841 ggaagctgaa gtaccagatg ctcaatggag aggtgtaccc gccatcggtg gaagaggcgc
901 ccgtgctgat gcactacccc cggggcatcc cgccccagag ccagatggct gtgggccagg
961 aggtgtttgg gctgcttcct gggctcatgc tctacgccac gatctggctg cgtgagcaca
1021 accgcgtgtg tgacctgctg aaggctgagc accccacctg gggcgacgag cagctcttcc
1081 agacggcccg cctcatcctc atcggggaga ccatcaagat tgtgatagag gagtatgtgc
1141 agcagctgag cggctacttc ctgcagctca agttcgaccc agagctgctg ttcggggccc
1201 agttccagta ccgcaaccgc atcgccatgg agttcaacca gctgtaccac tggcacccgc
1261 tcatgcccga ctccttccgg gtgggccccc aggactacag ctacgagcag tttctgttca
1321 acacctccat gctggtggac tacggggtcg aggccctggt ggacgccttt tctcgccagc
1381 ctgcaggccg gattggtggg ggtaggaaca tagaccacca catcctgcac gtggccgtgg
1441 atgtcatcaa ggaatcacgg gtgctgaggc tgcagccctt caatgagtac cgcaagaggt
1501 ttggcatgaa gccctacacc tctttccagg agctcacagg tgagaaggag atggcagctg
1561 aattggagga gctgtatgga gacatcgatg ctttggaatt ctacccgggg ctacttcttg
1621 agaagtgcca tccgaactcc atctttgggg agagtatgat agaaatgggg gctccttttt
1681 cccttaaggg cctcttagga aaccccatct gttctccaga gtactggaag gcgagcacat
1741 ttggcggtga ggtgggcttc aaccttgtca agacggccac gctaaagaag ctggtttgcc
1801 tcaacaccaa gacttgtccc tatgtctcct tccacgtgcc agacccccgt caggaggaca
1861 ggcctggggt ggagcggcca cccacagagc tctgaagggg ctgggcagca gcattctgga
1921 tggtagagct tcctgcttgc cattccagaa tgccacgggg tggattgtct ttgatgttgg
1981 gtttctgatt tggtgtcgag agcatcagtg tggacgttta gaactctagg tctctcaccc
2041 catggtctgg aatactgtgt tccttgtttg ttgttctaga atgctgaatt cctggtaaac
2101 cattgagaat gttaggagtg gttatccctt cagcattgcc agaacactgg gttcctgggt
2161 gaccacctag aatgtcagat ttctagttga tccggaattt aggcactctg aaatatggac
2221 tcctgatgga atcatctgga aagtgagggg gtttttattt tgcattctag aattctgggt
2281 ggccctccag aatgtcgact ttctgactgg ttatccggaa tgttgtgctc cgagttgctg
2341 atccagaaca gtggctggca ttctagatca gtcctgatcc gaatgtctag agtgttgaga
2401 attcattttc ctgttcagtg agacagccac ggagcaggag gatctcgtgt cctacaagaa
2461 cgcattgcct ggatctgtgc ctgcatggag agggcaagga agtggggtgt tcgtcttctc
2521 agtgggaccc ctgatgagac cctggatatg gagagaacag gtggctttct ccaggccatt
2581 ggttggaagc caccagagct ctgtcctcat ccaggtctca actcacggca gctgtttttc
2641 atgaagttaa taaaatgctt tttccg
//