LOCUS DME271350 4509
bp DNA
INV 08-FEB-2000
DEFINITION Drosophila melanogaster hex gene for hexokinase, strain
Oregon K.
ACCESSION AJ271350
VERSION AJ271350.1 GI:6729566
KEYWORDS hex gene; hexokinase.
SOURCE fruit fly.
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila.
REFERENCE 1 (bases 1 to 4509)
AUTHORS Deobagkar,D.D., Kulkarni,G.V. and Deobagkar,D.N.
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4509)
AUTHORS Deobagkar,D.D.
TITLE Direct Submission
JOURNAL Submitted (19-JAN-2000) Deobagkar D.D., University
of Pune,
Molecular Biology Research Laboratory, Department Of Zoology,
Ganeshkhind, Pune, Pune-411007. Maharashtra, INDIA
FEATURES
Location/Qualifiers
source 1..4509
/organism="Drosophila melanogaster"
/strain="Oregon K"
/db_xref="taxon:7227"
promoter 152..202
/gene="Hex"
gene
152..3958
/gene="Hex"
promoter 760..805
/gene="Hex"
CDS
881..2278
/gene="Hex"
/EC_number="2.7.1.1"
/codon_start=1
/product="hexokinase"
/protein_id="CAB72131.1"
/db_xref="GI:6911556"
/translation="MANTFNPEEDFPEVYKVCKLFNPSIDDLEKIKNAMDREITMGLS
RDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMMPTNCRIMLVKFSSERDIYTSSKCV
IMPHTVAAGRGTEVFTFLATSIANFVKEKKVDKDNLPLGIAFAFTLKKLALDVGILVS
WTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLALCWAQPDTRIGL
IMGSIANSCYVERVERCETYEGDEYRKLMIINSDWAHFGDTGQLDFIRNEYDRQLDTE
SINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEI
VSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMR
LPQISIAVDGGIYRLHPTFSTVLNKYTRLLADPNYNFEFVITQDSCGVGAAIMAGMAH
ANKYKTDAKLFTMDY"
mRNA
join(2320..3108,3122..3953)
/gene="Hex"
exon
2320..3108
/gene="Hex"
/number=1
CDS
2320..3075
/gene="Hex"
/EC_number="2.7.1.1"
/codon_start=1
/product="hexokinase"
/protein_id="CAB67701.1"
/db_xref="GI:6729567"
/translation="MTTYTFEFSMLLNFPCYSTRTSKARIEIYLMRKSTRLLTHSLFG
PVFKILFHNKTVCGGCNRKMPSLVNTEIEAAVKGFLIDQEKMTEVVERMTKEIKMGLA
KDTHARAVIKCFVSHVQDLPTGKERGKYLALDLGGSNFRVLLVNLISNSDVETMSKGY
NFPQTLMSGSGKALFDFLAECLSEFCHSHGLENESLALGFTFSFPLQQQGLSKGILVA
WTKGFSCEGVVGKNVVSFMAFKLFTCGSINIYI"
intron 3109..3121
/gene="Hex"
/number=1
exon
3122..3953
/gene="Hex"
/number=2
CDS
3194..3958
/gene="Hex"
/EC_number="2.7.1.1"
/codon_start=1
/product="hexokinase"
/protein_id="CAB72132.1"
/db_xref="GI:6911557"
/translation="MSCAFYHPNCRIGLIVGTGSNACYVEKTVNAECFEGYQTSPKPS
MIINCEWGAFGDNGVLEFVRTSYDKAVDKVTPNPGKQTFEKCISGMYMGELVRLVITD
MIAKGFMFHGIISEKIQERWSFKTAYISDVESDAPGEYRNCNKVLSELGILGCQEPDK
EALRYICEAVSSRSAKLCACGLVTIINKMNINEVAIGIDGSVYRFHPKYHDMLQYHMK
KLLKPGVKFELVVSEDGSGRGAALVAATAVQAKSKL"
BASE COUNT 1164 a 1043 c
1145 g 1157 t
ORIGIN
1 gatcgcctgc ctcctccgcc tacgcatcgc tctcctcgtc atcgaacagc cacagcagca
61 gtagcagtcc gggactggag ctggacagtc tggtgggatt gaacggaatc agcgccctgg
121 actctctgct tctggatacc tccgatggga ttccctctcc tgtctaagtc ccggctatgg
181 aagtctactc actggcagcg gggaatccct gttgcccggt tgccgaggtg atctgcccat
241 gtcgggtctg gagaagtcgg atgtggagct cagtctgcga ttactggacc agagttccaa
301 ggattccttc gactttgcca gcgatcagca gccgtcggcc tgtattagtt cgttctccgc
361 tctggatggg tatccattcg acctgctgca cagcgatttt ccggatatgt ttctcacgtg
421 acgcgtattt cttagcaacc ctaactactc tccttttaag cctaaccctc gtcttaagtt
481 agagtgcgag ttttaacccg actttcacta ttagccatta catgcgatgc gccattgagg
541 cggaattcat tgtgtcatag caagcagctg acaggataag tatattcaca tcctgcgaag
601 gcaaaagctg ctcaccgcca catccacatg atagctcaac tcaactagtg atttaagcat
661 ttctttgtga cgcatttctc gttatcctgt aaataaagca cccagtgttg attcaaacaa
721 tctattctgt gatgggattt tggatccttc aactttcaga gatatgaaac agagtagact
781 cttagattat tagttttaaa tggagcgatt ctgaaattga tattaggtag ccgcaatata
841 aatcatacct tatatttgag atcaatagac acacatcgaa atggcaaaca cttttaatcc
901 tgaggaggac tttccggaag tctacaaggt ctgcaagttg ttcaatccga gcatagacga
961 tcttgagaag attaaaaacg caatggatcg tgagattacg atgggtctga gtcgcgatca
1021 tcacgatcgt tcgaccgttc cgtgccactt gagctatgta caggatttgc caacgggcag
1081 ggagcgtggt cagttcttgg ccctggagat gatgcccact aactgcagga taatgctggt
1141 gaagttcagc agcgagagag atatctacac cagttccaag tgcgtgatta tgccgcatac
1201 tgtggcagcg ggtcgaggaa ccgaggtctt cacctttctg gccaccagca tagcaaattt
1261 tgtgaaggag aaaaaggtgg acaaggacaa tctgccgctg ggcatagcct ttgcctttac
1321 cctaaagaag ttggctttgg atgtgggtat ccttgtgtcg tggaccaagg agtttggagc
1381 ccaaggcgcc atcggcaagg atgtggtcca actgctgcgc gatgctctgg ccaagtttcc
1441 cgaaatctcc gtcgatgtca tgggtatcat caatgtcgga gccggttcgc tgctggctct
1501 gtgctgggcc caaccggata cccgaattgg cttgatcatg ggcagtattg ccaatagctg
1561 ttatgtggaa agggtcgaaa ggtgcgaaac gtacgagggt gatgagtaca gaaagctgat
1621 gatcattaac tcggattggg cccatttcgg ggatactggg cagttggatt tcatacgtaa
1681 cgaatacgat cgccagctgg acaccgagtc cataaatccg ggcactcgga tctatgagaa
1741 gtttagtgga gctctttgca tgggagaatt ggttcgcatt atagtgcttc gcctgatgaa
1801 atcgggcgcc atctttgccg aggacaggcg tgattacata gggatccagt ggaagttgga
1861 catggtgtcg ctgatcgaaa tcgtctcgga tccgccgggt gtctatacga aggcacagga
1921 ggtgatggac aagtttcgca tacgtcactg caaggaacgg gatctggctg ccttgaaata
1981 catctgcgac acggtcacaa atcgtgctgc catgctggtg gccagtggag tttcctgcct
2041 cattgaccgc atgcgcttgc cacagatctc gatcgccgtg gatggcggca tctaccgcct
2101 tcatccgacc ttttccaccg ttcttaataa gtacacccgt ttgctagccg atcccaatta
2161 caacttcgag tttgtcatca cccaggacag ctgcggagtg ggagcggcca taatggcggg
2221 aatggcacat gccaacaagt acaaaacgga cgcgaaattg tttactatgg actactagat
2281 atgcataaat aaaattttta ttatgtctgc ttaaatacaa tgacaacata tacgtttgaa
2341 ttttccatgt tgttaaattt tccatgttat tcaaccagaa cgtccaaagc aagaattgaa
2401 atttacctca tgagaaagtc aactagactt ttaactcatt ctctattcgg ccctgtattt
2461 aaaattttgt ttcataacaa aacagtttgt ggaggctgta ataggaaaat gccgagcctg
2521 gtgaacacgg aaattgaagc cgcggtcaag ggcttcctga tcgaccagga gaagatgacc
2581 gaggtggtgg agcgcatgac caaggagata aagatgggcc tggccaagga cacgcatgca
2641 cgagcggtga tcaagtgctt cgtcagccat gtgcaagatc tgcccactgg caaggagcgg
2701 ggaaagtatt tggccctgga tctgggtggc tctaatttca gggtgcttct ggtgaacctg
2761 attagcaact cggacgtgga aaccatgtcg aagggctata attttcctca aactctgatg
2821 tccggatcgg gaaaggcgct tttcgacttc cttgccgaat gcctgtcgga gttttgtcac
2881 tcccatggcc tggagaatga atcactggct ctgggcttca ccttctcgtt tccgctccag
2941 cagcagggac tctccaaggg tatccttgtg gcctggacca aaggattcag ctgcgaaggc
3001 gtggtgggca agaatgtggt gagtttcatg gcgttcaaac tatttacgtg tggttctatt
3061 aacatttata tttaacaaat gaatttcttt taatatgcat tcctaggtga gtcttctcca
3121 ggaggcaatc gatcgaaggg gcgatctaaa gatcaatacc gtcgccattc tcaacgatac
3181 ggtgggcact ctgatgtcct gcgccttcta tcatcccaac tgccggattg gattgatcgt
3241 gggaaccggc tccaatgcgt gctatgtgga gaaaacagta aatgccgaat gcttcgaagg
3301 ataccagacc agtcccaagc catcaatgat aatcaactgc gagtggggcg cctttgggga
3361 caatggtgtt ctggagttcg ttcgaacttc ctacgacaag gcagtcgaca aggtaacacc
3421 caatcccggc aagcagacgt tcgaaaagtg catatcgggc atgtatatgg gtgaacttgt
3481 acgtttggtc atcaccgata tgattgccaa gggttttatg ttccacggca tcatttccga
3541 gaagatccag gagcgatgga gcttcaaaac cgcctatatt tccgatgttg aaagtgatgc
3601 acctggcgag tatcgcaatt gcaataaggt ccttagcgaa ttgggcatat tgggctgcca
3661 ggaacccgac aaagaggccc tgcgatacat ctgcgaggcg gtgtcctcca ggtctgccaa
3721 gctatgtgcc tgcggcctgg tcaccattat caacaagatg aacatcaacg aggtggccat
3781 cggcatagac ggtagcgtgt atcgcttcca tcccaagtac cacgacatgc tccagtacca
3841 catgaagaag ctcctcaagc cgggcgtcaa gtttgagctg gttgtttcgg aggacggatc
3901 cggaagagga gcggctctcg tggcggccac cgcagtccag gccaaaagca agctctaaat
3961 tcgaagttga tattcttcaa atgcatggga aacgttacgg acaatgatat atgagcacaa
4021 aattatggaa gaagaaataa agatttaagg atataatggg aacttttaat attatccttt
4081 caaacttaaa attgtgtcca gaaatccgat ttgaattatg gcgccaaaga tataataatt
4141 ttctgcctta gtggcaacac tgcacatcca tagtattttt tagtacatgc agtattttta
4201 gaatatttat ggaacgatag ggatggggta acactatttt ggtataaaag ccaactcgcc
4261 atctggtaac acttggagtt tgcaaacatt tatctctcga ccaatttaag gaatttgagg
4321 caattagggc attcctgtga gcttttccag gccaactgcg attacttcaa gccaagacaa
4381 acaggtgggt aaccaagcag gccgtgcccc accgaccaga ccagcaaaac acccccattt
4441 cgggcggtgc tggaaaaagc aaggccagct gtccatttgg gatttggaca ctccactctg
4501 agcatcaag