LOCUS       HSHKRI1      1061 bp    DNA             PRI       03-FEB-1998
     DEFINITION  Homo sapiens hexokinase (HK) gene, isozyme R, partial cds.
     ACCESSION   AF029306
     VERSION     AF029306.1  GI:2827144
     KEYWORDS    .
     SEGMENT     1 of 2
     SOURCE      human.
       ORGANISM  Homo sapiens
                 Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
                 Eutheria; Primates; Catarrhini; Hominidae; Homo.
     REFERENCE   1  (bases 1 to 1061)
       AUTHORS   Murakami,K. and Piomelli,S.
       TITLE     The erythrocyte-specific hexokinase isozyme (HKR) and the common
                 hexokinase isozyme (HKI) are produced from a single gene by
                 alternate promoters
       JOURNAL   Blood 90 (10), 272a (1998)
     REFERENCE   2  (bases 1 to 1061)
       AUTHORS   Murakami,K. and Piomelli,S.
       TITLE     Direct Submission
       JOURNAL   Submitted (08-OCT-1997) Pediatrics, Columbia University, 630 West
                 168th Street, New York, NY 10032, USA
     FEATURES             Location/Qualifiers
          source          1..1061
                          /organism="Homo sapiens"
                          /db_xref="taxon:9606"
                          /chromosome="10"
                          /map="10q22"
          mRNA            697..>876
                          /gene="HK"
                          /note="isozyme R"
                          /product="hexokinase"
          CDS             817..>876
                          /gene="HK"
                          /note="isozyme R"
                          /codon_start=1
                          /product="hexokinase"
                          /protein_id="AAC00172.1"
                          /db_xref="GI:2827147"
                          /translation="MDCEHSLSLPCRGAEAWEIG"
     BASE COUNT      277 a    213 c    347 g    224 t
     ORIGIN
             1 cccttctaac ctcaccaggc tgttatcagg agaaatgaag caataaatga gaaattgctg
            61 tgcaaactgt caacgttatg taaacattgc tattcagagt gtgctcccag gtgcgggagg
           121 tacagctgtt atctgttgga gatcactcct gaagtaacat tcctagtgcc atgggtcaga
           181 tgggaattgg tacagacatt ccaacttaga aggcagcctt tattgtctta taagcaggtg
           241 cgtttcctgg ggtggcagcc tggcactggt cactccaacc ccaacttgtg taggaggtac
           301 cacagtaaat gagtagagag agttcagggg acttgaaggg aagtggaggg ccatctggag
           361 agggagggaa ctaaggactc cctgtgggtt gggtcttcct gaggatccag ggagtaactg
           421 tcaaggagcc ttagcaggga tctaagagct atgcaagagc aaaaagaggc aaattattaa
           481 ggaaattagt gaagtcagca ctggaacaac agagagggga cacagcagtg cagcatgggc
           541 cctggcctca ggaagctgtc tgattggggc agataggacc agccccctag aagacagtca
           601 cccatatcag ttaggcagtc atgactcagt gttacttatc tgaggcccag gttgcatgag
           661 gggttggggg tgggatggac agagcactgg ctgggcatca ggactaggct ggagtcctgg
           721 ctcaaaactc taccacaacc tgacactggg caagatggcc cacctgtggc atcccaggtt
           781 cctgccctgt aaagaggagt ctgggtgtat atccagatgg actgtgagca cagcctgagt
           841 ttgccctgtc gaggtgctga ggcctgggag attggggtga gtagctgtgg tccagggaag
           901 gttggcaagc tgggccttag atgagagggg atgcttggtc acgcagaggt gagtggagaa
           961 cgcagggcaa ggaacggaat atgagcggcg aacaaatgga gtggacatgg tgggggcaca
          1021 agatggtggg aagtggcctt gttgcggcca cagtggaaga a
     //
     LOCUS       HSHKRI2       515 bp    DNA             PRI       03-FEB-1998
     DEFINITION  Homo sapiens hexokinase (HK) gene, isozyme I, partial cds.
     ACCESSION   AF029305
     VERSION     AF029305.1  GI:2827145
     KEYWORDS    .
     SEGMENT     2 of 2
     SOURCE      human.
       ORGANISM  Homo sapiens
                 Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
                 Eutheria; Primates; Catarrhini; Hominidae; Homo.
     REFERENCE   1  (bases 1 to 515)
       AUTHORS   Murakami,K. and Piomelli,S.
       TITLE     The erythrocyte-specific hexokinase isozyme (HKR) and the common
                 hexokinase isozyme (HKI) are produced from a single gene by
                 alternate promoters
       JOURNAL   Blood 90 (10), 272a (1998)
     REFERENCE   2  (bases 1 to 515)
       AUTHORS   Murakami,K. and Piomelli,S.
       TITLE     Direct Submission
       JOURNAL   Submitted (08-OCT-1997) Pediatrics, Columbia University, 630 West
                 168th Street, New York, NY 10032, USA
     FEATURES             Location/Qualifiers
          source          1..515
                          /organism="Homo sapiens"
                          /db_xref="taxon:9606"
                          /chromosome="10"
                          /map="10q22"
          gene            order(AF029306.1:1..1061,1..>515)
                          /gene="HK"
          mRNA            248..>391
                          /gene="HK"
                          /note="isozyme I"
                          /product="hexokinase"
          CDS             329..>391
                          /gene="HK"
                          /note="isozyme I"
                          /codon_start=1
                          /product="hexokinase"
                          /protein_id="AAC00173.1"
                          /db_xref="GI:2827148"
                          /translation="MIAAQLLAYYFTELKDDQVKK"
     BASE COUNT       68 a    197 c    193 g     57 t
     ORIGIN
             1 tgcgtcgccg ccccctttcc ggcgcaggag ggagcggccg ccgcgtcccc gctccccggc
            61 cgggacgcca ccgccgggcg ttgcagaggc gcgccgcaac caatgggcgt ggaggaggtg
           121 ggtcggctgg cggctgtcac cctccagggg acgggagcgc ggagaccggg agcgcgcgag
           181 ctgtcgccgc gccccgggcc gagggggagg agccggggga ggaggaggag gaggagccgc
           241 cgagcagccg ccggaggacc acggctcgcc agggctgcgg aggaccgacc gtccccacgc
           301 ctgccgcccc gcgaccccga ccgccagcat gatcgccgcg cagctcctgg cctattactt
           361 cacggagctg aaggatgacc aggtcaaaaa ggtgagcccc cgcccgcgcc gccgctggtc
           421 ctggccgcag ccttgcgttc cggcatccgc tcgccgcctc cgctgcgtcc atcctccggc
           481 gcccggcctt ctccgggcca gcatcgagtt ggact