LOCUS RATPPLCA 5106 bp mRNA ROD 13-NOV-1991
DEFINITION Rat phospholipase C mRNA, complete cds.
ACCESSION J03806
NID g206323
KEYWORDS phospholipase C.
SOURCE Rat brain cDNA to mRNA.
ORGANISM Rattus norvegicus
Eukaryotae; mitochondrial eukaryotes; Metazoa; Chordata;
Vertebrata; Eutheria; Rodentia; Sciurognathi; Myomorpha; Muridae;
Murinae; Rattus.
REFERENCE 1 (bases 1 to 5106)
AUTHORS Suh,P.-G., Ryu,S.H., Moon,K.H., Suh,H.W.
and Rhee,S.G.
TITLE Inositol phospholipid-specific
phospholipase C: Complete cDNA and
protein sequences and sequence homology to tyrosine kinase-related
oncogene products
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85, 5419-5423
(1988)
MEDLINE 88289733
COMMENT Draft entry and computer readable copy
of sequence [1] kindly
submitted by S.G.Rhee 14-SEP-1988.
FEATURES
Location/Qualifiers
source
1..5106
/organism="Rattus norvegicus"
/db_xref="taxon:10116"
CDS
95..3967
/note="phospholipase C"
/codon_start=1
/db_xref="PID:g206324"
Translation="MAGVGTPCANGCGPSAPSEAEVLHLCRSLEVGTVMTLFY
SKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRD
FDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGL
TWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQV
NYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPF
LETNTLRTGERPELCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFL
RDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYW
ISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIY
HGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHF
RKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSV
MYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGN
EDEEEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAP
DGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVF
DSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAE
HMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGN
SEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRN
PGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWW
RGDYGGKKQLWFPSNYVEEMINPAILEPEREHLDENSPLGDLLRGVLDVPA
CQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQT
ADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFP
ETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQL
VALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGL
EPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNP
VWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAV
PLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERASDASSQLFHVRA
REGSFEARYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL"
BASE COUNT 1209 a 1350 c
1455 g 1092 t
ORIGIN 434 bp upstream of EcoRI site.
1 cgctcgcctc ccgggccgcc
gccgccgcct ccgcctccgc ctccgcctcc gccgccccgg
61 gcccgccggc ttgcgtcgcc gaggtcgctg
cagcatggcg ggcgtcggga ccccctgcgc
121 caacggctgc gggcccagcg cgccctccga
agcggaggtg ctgcacctct gccgcagcct
181 cgaggtgggc accgtcatga ctttgttcta
ctccaagaag tcgcagcggc cagaacggaa
241 gaccttccag gtcaagttgg agacgcgcca
gatcacatgg agccgcggtg cggacaaaat
301 cgaggggtcc atcgatatcc gagaaatcaa
ggagatccgc ccagggaaga cttcccggga
361 ctttgaccgc taccaagaag accctgcctt
ccggccagat cagtcacact gttttgtcat
421 cctctatgga atggaattcc gcctgaagac
cctgagcctg caagccacat ctgaggatga
481 agtgaacatg tggatcaagg gcttaacttg
gctcatggaa gatacgctgc aggcggccac
541 acccctgcaa attgagagat ggctccggaa
gcagttctac tcagtggatc gtaaccgaga
601 ggatcgtata tcagccaagg acctgaagaa
catgctgtca caggtcaact accgggtccc
661 caacatgcgc ttcctccgag agcggctgac
ggactttgaa cagcgcagcg gggacatcac
721 ctatgggcag tttgctcagc tttaccgcag
cctcatgtac agcgcccaga agacgatgga
781 ccttccgttc ttggaaacca acactttgag
gactggagag cggccagagc tttgccaggt
841 gtccctttct gagttccagc agttccttct
tgagtaccag ggggagctgt gggctgtcga
901 ccggcttcag gtgcaggaat ttatgctcag
cttccttcga gaccccttgc gagagattga
961 ggagccatac ttcttcttgg atgagcttgt
cacctttctg ttctccaaag agaacagtgt
1021 gtggaactca cagctggatg ccgtgtgccc agaaaccatg
aacaacccac tgtctcacta
1081 ttggatctct tcctcgcata atacgtatct gactggggac
cagttctcca gcgagtcctc
1141 cctggaagcc tacgctcgct gcctgaggat gggctgtcgc
tgcatcgagt tggactgctg
1201 ggatgggcca gatgggatgc cagtcattta ccatgggcac
accctcacca ccaagattaa
1261 gttctcagat gtcctgcaca ccatcaagga gcacgcgttc
gtagcctcag agtaccctgt
1321 catcctgtcc atcgaggacc actgcagcat tgcccagcag
aggaacatgg cccagcactt
1381 caggaaggtg ctcggtgaca cgctcctcac caagcccgtg
gacattgccg ctgatgggct
1441 cccttctccc aaccagctca agaggaagat cctgattaag
cataagaagc tggctgaggg
1501 cagtgcctat gaggaggtgc ctacctctgt gatgtactct
gagaatgaca tcagtaactc
1561 catcaagaat ggtatcctct acttggagga ccccgtgaat
catgagtggt acccccacta
1621 ctttgttctg actagcagca agatctacta ctctgaggag
accagcagtg accagggaaa
1681 tgaggatgaa gaggagccga aggaggccag tggcagcaca
gagctgcact cgagcgagaa
1741 gtggttccac gggaagctcg gggctgggcg cgacgggcgg
cacattgctg agcgcctgct
1801 caccgagtac tgcatagaga ctggggctcc cgatggctcc
ttcctagtgc gagaaagtga
1861 gaccttcgtg ggggactaca cgctgtcttt ttggcggaat
gggaaagtcc agcactgccg
1921 tatccactcc cggcaggatg ctgggactcc taagttcttc
ttgacagata accttgtctt
1981 tgactctctc tatgacctca tcacacatta tcagcaagtg
cccctgcgct gcaatgagtt
2041 tgagatgcgc ctttcagagc ctgttccaca gacgaatgcc
catgagagca aagagtggta
2101 ccacgcaagc ctgactagag ctcaggctga acacatgctg
atgcgagtac cccgtgatgg
2161 ggccttcctg gtgcggaagc gcaacgagcc caactcctat
gccatctctt tccgggctga
2221 gggaaagatc aagcactgcc gagtacagca ggaaggccag
actgtgatgc tggggaactc
2281 tgagtttgac agcctggtcg acctcatcag ctactatgag
aagcatcccc tgtaccgcaa
2341 aatgaaactg cgctacccca tcaacgagga ggcgctggag
aagattggga cagctgaacc
2401 cgattatggg gcactgtatg agggccgcaa ccctggtttc
tatgtggagg ccaaccctat
2461 gccaactttc aagtgtgcag taaaagctct cttcgactac
aaggcccaga gagaggatga
2521 gctgactttt accaagagcg ccatcatcca gaatgtggaa
aagcaagatg gtggctggtg
2581 gcgtggggac tatggtggga agaagcagct gtggttcccc
tcaaactatg tggaagagat
2641 gatcaatcca gcaatcctag agccggagag ggagcatctg
gatgagaaca gcccactggg
2701 ggacttgctg cgaggggtct tagatgtgcc agcctgccag
atcgccattc gtcctgaggg
2761 caaaaacaac cggctcttcg tcttctccat cagcatgccg
tcagtggctc agtggtccct
2821 agacgttgcc gctgactcac aggaggagtt gcaggactgg
gtgaaaaaga tccgtgaagt
2881 tgcccagact gcagatgcca ggcttactga ggggaagatg
atggagagga ggaagaagat
2941 cgccttggag ctctccgagc tcgtggtcta ctgccggcct
gttccctttg acgaagagaa
3001 gattggcaca gaacgcgctt gttaccggga catgtcctcc
tttccggaaa ccaaggctga
3061 gaagtatgtg aacaaggcca aaggcaagaa gttcctccag
tacaaccggc tgcagctctc
3121 tcgcatctac cctaagggtc agaggctgga ctcctccaat
tatgaccctc tgcccatgtg
3181 gatctgtggc agccagcttg tagctctcaa ttttcagacc
ccagacaagc ctatgcagat
3241 gaaccaggcc ctcttcatgg ctggtggaca ctgtggctat
gtgctgcagc caagcaccat
3301 gagagatgaa gcctttgacc cctttgataa gagcagtctc
cgaggtctgg agccctgtgt
3361 catttgcatt gaggtgctgg gggccaggca tctgccgaag
aatggccggg gtattgtgtg
3421 tcctttcgtg gagattgaag tggctggggc agagtacgac
agcaccaagc agaagacaga
3481 gtttgtagtg gacaatggac tgaaccctgt gtggcctgca
aagcccttcc acttccagat
3541 cagtaaccca gagtttgcct ttctgcgctt tgtggtgtat
gaggaagaca tgtttagtga
3601 ccagaacttc ttggctcagg ctactttccc agtaaaaggc
ctgaagacag gatacagagc
3661 agtgcctttg aagaacaact acagtgaaga cctggagttg
gcctccctgc tcatcaagat
3721 tgacattttc cctgctaagg agaatggtga cctcagccct
ttcagtggta catccctaag
3781 ggaacgggcc tcagatgcct ccagccagct gttccatgtc
cgggcccggg aagggtcctt
3841 tgaagccaga taccagcagc catttgaaga cttccgcatc
tcgcaggagc atctcgcaga
3901 ccattttgac agtcgggaac gaagggcccc aagaaggact
cgggtcaatg gagacaaccg
3961 cctctagtca tgcccctacc ttgttggaga gcagcagcgc
tgccacctgt ggaatgccat
4021 gaactgggtt ctctgggagc ggtctactgt aaagccttcc
tggtctcaca gcctggagcc
4081 tggattccag cggtgaaggc tagacaaaac caagccatta
atgagatgta ctgttttggg
4141 cctccatgcc cagctctggg tgaaggcaaa aaactgtact
gtgtctcgca ttaagcacac
4201 acatctggcc ctgaatgtgg aggtgggtcc ctccatcttg
ggccaggact agggctgaag
4261 ccccttggaa agagaagttg cctcagttgg tggcatagga
agcttcaagg agctgctgac
4321 acattcctga aagaggaaga ggaggaggag gaagagcctt
gctgggccag gggaacaaag
4381 tttacattgt cctgtagctt taaaaccaca gctggtcagg
gtgaaagagt agatgccctg
4441 aggcttggcc ctggagccag gtcagaggaa tgcagggcct
gtaaggagaa ggctctgctc
4501 tgcctgagga ggaagacagc acaagggcac attgccaccg
tgggtatact acccagcctg
4561 aaagatacag gggatcatga taaatagcag tattattttt
ttttttcttc tcagtggtat
4621 tgtgactaag ttattctgtc ctgctcctca ccttggaagg
gaagacccag cacagagcct
4681 ttaggaacag cagctctatg gggtgttgtt actggaagag
ggcactgtcc agaagggtgg
4741 aggggcagaa agagagaaaa tcgatgtcta ccctggtgag
cgtttttgtt tttatggcaa
4801 ggaaggctca ttatgctctc ccaaaggaat ggagacatgg
gtaagtggag tcaggcagta
4861 ggcaccaaat gaagctgctg cttggtagtc tctgtgtggt
tggtaaaaag atgcaaagga
4921 gatgggaagg taagcctcac ctctgaggac agggtggggt
ccaggcctgt gggtgcaaag
4981 gtgcctcagc atagccagca ttcagcacac gcaaacccac
tgcccacatt tgggctcagg
5041 gttggccatt tgctagttct gctgccctct taagatctga
ctgccaaata aatcatcctc
5101 atgtcc