LOCUS       GGDMIACK     3946 bp    DNA             VRT       13-SEP-1996
DEFINITION  G.gallus Mia-CK gene.
ACCESSION   X96402
NID         g1545941
KEYWORDS    Mia-CK gene; mitochondrial creatine kinase.
SOURCE      chicken.
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Vertebrata; Archosauria; Aves;
            Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 3946)
  AUTHORS   Muhlebach,S.M., Wirz,T., Brandle,U. and Perriard,J.C.
  TITLE     Evolution of the creative kinases. The chicken acidic type
            mitochondrial creatine kinase gene as the first nonmammalian gene
  JOURNAL   J. Biol. Chem. 271 (20), 11920-11929 (1996)
  MEDLINE   96216114
REFERENCE   2  (bases 1 to 3946)
  AUTHORS   Muehlebach Markus,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-MAR-1996) S. Muehlebach Markus, ETH Zuerich, Biology,
            Institute for Cell Biology, ETH Hoenggerberg, CH-8093 Zuerich,
            Switzerland
FEATURES             Location/Qualifiers
     source          1..3946
                     /organism="Gallus gallus"
                     /strain="white leghorn"
                     /db_xref="taxon:9031"
                     /clone_lib="EMBL3"
                     /dev_stage="adult"
                     /tissue_type="liver"
     intron          <1..839
                     /number=1
     prim_transcript <1..3861
     exon            840..1038
                     /number=2
     mRNA            join(840..1038,1156..1251,1338..1559,1961..2046,
                     2567..2690,2832..2966,3260..3385,3616..3861)
     gene            877..3732
                     /gene="Mia-CK"
     CDS             join(877..1038,1156..1251,1338..1559,1961..2046,
                     2567..2690,2832..2966,3260..3385,3616..3732)
                     /gene="Mia-CK"
                     /EC_number="2.7.3.2"
                     /note="acidic-type"
                     /codon_start=1
                     /product="mitochondrial creatine kinase"
                     /db_xref="PID:e229338"
                     /db_xref="PID:g1545942"
                     /db_xref="SWISS-PROT:P70079"
                     /translation="MASNLTPAIYARLCDKATPNGWTLDQCIQTGVDNPGHPFIKTVG
                     MVAGDEETYEVFAELFDPVIQERHNGYNPRTMKHVTDLDASKIKFGHFDERYVLSSRV
                     RTGRSIRGLSLPPACTRAERREVEKVTVEALNGLTGDLSGRYYRLSEMTEKEQQQLID
                     DHFLFDKPVSPSLTAAGMARDWPDARGIWHNNEKTFLIWINEEDHTRVISMEKGGNMK
                     RVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHIKLPLLSKD
                     SRFPKILENLRLQKRGTGGVDTAATANVFDISNLDRLGKSEVELVQLVIDGVNYLIDC
                     ERRLEKGQDIRIPSPVPQFRH"
     intron          1039..1155
                     /gene="Mia-CK"
                     /number=2
     exon            1156..1251
                     /gene="Mia-CK"
                     /number=3
     intron          1252..1337
                     /gene="Mia-CK"
                     /number=3
     exon            1338..1559
                     /gene="Mia-CK"
                     /number=4
     intron          1560..1960
                     /gene="Mia-CK"
                     /number=4
     exon            1961..2046
                     /gene="Mia-CK"
                     /number=5
     intron          2047..2566
                     /gene="Mia-CK"
                     /number=5
     exon            2567..2690
                     /gene="Mia-CK"
                     /number=6
     intron          2691..2831
                     /gene="Mia-CK"
                     /number=6
     exon            2832..2966
                     /gene="Mia-CK"
                     /number=7
     intron          2967..3259
                     /gene="Mia-CK"
                     /number=7
     exon            3260..3385
                     /gene="Mia-CK"
                     /number=8
     intron          3386..3615
                     /gene="Mia-CK"
                     /number=8
     exon            3616..3861
                     /number=9
     polyA_signal    3843..3848
     polyA_site      3861
BASE COUNT      775 a   1233 c   1189 g    749 t
ORIGIN
        1 acccagattt gctcatggac tcttgtcctt gtggcaacca tcagctgggg ctgctctctg
       61 ctcccatgca atgccagcag ctctctttgt ggggacagca tggctctccc tgcccaccct
      121 gctgcggggg tctccatagg gcaggggcac cactggggcc tggagtggat gacagttgat
      181 ggccgctcag cagcactcac tgccctcact ctcactccct agggagacaa gagggagaaa
      241 tgccaggaaa aaaagtttgt aggtgtcaca ctcacccata agggaagggg tgactggatt
      301 cgcaatttgg tccttaacag tggggttgag ataaagagta gtttaatgaa agggaggaaa
      361 aaagaacaaa ggtcatgcag aagtaaaagg aaaatatata tttattcttg attttccatc
      421 agtaaagcaa tgctcagcca ctcattggga agcagggcct cgggatacgc agcagtcact
      481 tgggcagatg gacgctctcg taatgagagc ccttccttct ccctgccccc aacttttatt
      541 gctgaatgcg atgtgtgcag tatggaatat gccctggttg ggttaggccg gctgccccag
      601 ggatgtctcc tccccacctc ctgcccatac ccacccaggc tttgcaggac tggggaggac
      661 cgtgatgctg tgccagtgct gctaggtagg agacagaacg ttggtgccat ttcagtgcca
      721 ccgtagctat ggatgtaacc cacagcactg tgggctgcag tgaggaaatg agctccaacc
      781 caggcagact cggcacagaa ctgctggaca caaaggctca ttggtgcccc ctcccgcagt
      841 gctgagtacc ccgacctgcg gaaacacaac aactgcatgg ccagcaacct gacgccagcc
      901 atctacgcac ggctctgtga caaagccacc cccaacggct ggaccttgga ccagtgcatt
      961 cagaccggcg tggacaaccc aggccaccct ttcatcaaga cagtgggcat ggtggctggt
     1021 gatgaggaga cgtatgaggt aagacacggc cggggccctg ccacgctcca ggctccatcg
     1081 ggcacctgcc ccatccccca gcaggctctg catgacgctg gctctgaaga gctgccctgt
     1141 cctgctcccc cccaggtgtt tgcagagctg tttgaccccg tgatccagga gcggcacaac
     1201 gggtacaacc cccgcaccat gaagcacgtc acggacctgg acgcctccaa ggtgggcacg
     1261 gtgccgcgtg ccctggcctt ggggactgtg atgcttcagt gctagctctg cccaccaacg
     1321 tcccccgttt gttctagatt aagtttggcc acttcgatga gcgctacgtg ctctcatccc
     1381 gggtccggac cgggcgcagc atccgtgggc tgagccttcc acccgcctgc acccgtgccg
     1441 agcggcggga ggtggagaag gtgacggtgg aggctctgaa tggcctcaca ggggatctgt
     1501 cgggccgcta ctaccgtctc agcgagatga cagagaagga gcagcagcag ctcattgatg
     1561 tgagtcgggc agccctggta ggacgccatc ctagtaccac ctcccaccat ttctccctcc
     1621 cccagcccaa gccctgcaga accgggcact gtccccagtg cggttgcccc atgctgcaga
     1681 ggctacttat ggccccactc ataagaagaa gatggagttg aatgcggccc cagcagctca
     1741 tggggctctc tggctcccgc ccggtgtccc tccacatgcc cagggaaagg cgagtgcatg
     1801 gcacgtggct gctagccttc tggcactgtg agggatgcac acccacaacc tctgcacagg
     1861 gacagccagt gacgttcacc tcctgtgtgg tgcacgggga ccagagggac ggcgccccgg
     1921 tatccaccac gtgccctact gacacgctgt gtccctgcag gaccacttcc tctttgacaa
     1981 gccggtgtcc ccgtctctga cggcagcagg aatggcccgg gactggcctg acgcccgagg
     2041 catctggtga ggacctgcct ggcgttgggc caccaaaagg gcaggaggag gagggcactg
     2101 ctgctccatc ctgctgtccc cacccgcgct cccagcccca cagaccccgg tgactccagg
     2161 ctgccattcc ccagctccgt gtgcacggct gtgttctcca tgcccacccg cagcctggct
     2221 tcctatctcc ggctgcagcc catggagctg tgcagagccg ggggcagccg ctccctgcac
     2281 agtccgcagc accttgcatg gcagcgggca gctctgcagc catcccaggc cctgctgcca
     2341 gccctgcctg ctttgcggca catcgttccc tctgctgaca aaaacctgtg cctgctggct
     2401 gcttcccaga taatgcccag cactccaccc cactctgcac actgtacccg cccccaaatt
     2461 tacgcggcca cagctgcttc tccctcctgc tcccagctgc tgctgctggc agcgtgggca
     2521 cagggctcta ctagcctccg cgcagccgag cactgctctg tcccaggcac aacaatgaga
     2581 agaccttcct gatctggatc aacgaggagg accacacgcg cgtcatctcc atggagaagg
     2641 gtggtaacat gaagcgcgtc tttgagcggt tctgccgggg cctgaaggag gtgagcaacc
     2701 tctgcgctac cttgccagcc ccctgcggat gggggccctg caggacgcgt gtccctcgca
     2761 gtctcagggc tgggcagcac cacgctgagg gctgggctgg cactgagctg ctttctgtgc
     2821 ctctaaccca ggtggagcga ctaatccagg agcgaggctg ggagttcatg tggaatgaga
     2881 ggctgggcta catcctgacc tgcccctcca acctgggcac cgggctgcgg gcaggtgtcc
     2941 acatcaagct gccactgctc agcaaggtaa tggctgtgga cggtgctggg ggagccggga
     3001 ttgcaggcac agggagccca gccctgccag gatgagagga ctgtatggca cagccctggg
     3061 tgctgcttgg gatcacacag gggagcagag cagtgcatgg tgcccacatt gcagctggag
     3121 gggccaggca cacgtgtgct gagtgggatc tgcttgggcc cagggactgc agggctacag
     3181 acagggtgct gcagggtgtg ggagggtggt cctggggagc tgtcatttgc tgatggttct
     3241 gctgatctct gggcaccagg acagccgctt ccccaagatc ctggagaacc tgcggctaca
     3301 gaagcgtggg acaggcggtg tggacacagc agccaccgcg aatgtcttcg acatctccaa
     3361 cctggaccgg ctggggaagt cagaggtggg agaggggcga agctgctctt ggcaagggca
     3421 gttgggaaca cgtgcgcaca cctcagcacc agaacagctt tgcagctgta tgctgaagcc
     3481 agcagtgggg tctaggagct gcactgtgct ccatgggtgc cgtaggtgcc ctttacacag
     3541 cggctgctgg caccgctcgg ggggctggcc ggggccagga cagcttcgag tcagaacttt
     3601 gtgctcctcg tgcaggtgga actggtgcag ctggtgatag acggtgtgaa ctacctgatc
     3661 gactgcgagc ggcggctgga gaagggtcag gacattcgca tcccctcccc agtaccacag
     3721 ttccggcact gagccacgcc gaggcagcgc cagccctgca ggacccagct tcccccatag
     3781 cttatgccat caatgcgccc agcatgtcgc tgtgctgtta cacacagagc caggccagac
     3841 cccataaaca tgtgctgctg agccttggct ctctctgctc cttaccccac ctggccctgt
     3901 gcccgcatga gaggcacaca gatgggtctt gatatccttg agtagc
//