Heliocidaris erythrogramma Genes in Development:
Homeobox Genes
HeHB19
Function
HeHB19 is an unusual homeobox-containing gene, similar to the C. elegans
gene ceh-19, which contains a homeobox unlike any other described so far.
Thus far ceh-19, the sole representative of a distinct class
of homeobox-containing genes, has only been known in nematode.
If HeHB19 is not actually the homologue of ceh-19, then it is the second known member of this class of homeodomain encoding genes
(Popodi et al., 1995).
Protein
The deduced amino acid sequence shows 77% identity to the first
53 amino acids of the homeodomain of the ceh19 gene product.
Both genes specify an unusual Thr49 of this domain.
In addition, 3 of 7 amino acids just upstream from the homeodomain are
identical (Popodi et al., 1995).
GenBank: 710352