Strongylocentrotus
purpuratus Genes in Development: Receptors
SpSHR2
Function
SpSHR2 gene codes for a transcription factor which belongs to the superfamily of steroid-thyroid-retinoic acid
hormone receptors.
Genomic DNA hybridization suggests that SpSHR2 is
a single-copy gene (Kontrogianni-Konstantopoulos et al., 1996).
Protein
The SpSHR2 antibodies recognize the single polypeptide
with an apparent size of about 75 kDa (Kontrogianni-Konstantopoulos et al., 1996).
Subcellular location
Expression Pattern
SpSHR2 transcripts are stored in the egg
as maternal RNAs in different forms resulting from alternative
splicing and disappear before gastrulation without being
replaced by embryonic RNAs.
During early cleavage stages
of embryonic development the SpSHR2 protein is synthesized
by translation of the maternal RNA (Kontrogianni-Konstantopoulos et al., 1996).
mRNA level
Temporal accumulation
Method: RT-PCR analysis
Reference: Kontrogianni-Konstantopoulos et al., 1996.