LOCUS HUMPGHS 1972 bp DNA PRI 28-NOV-1994
DEFINITION Human clone DMPC-HFF1-1415B prostaglandin synthase-2 (PGHS-2) gene,
promoter region.
ACCESSION L34209
VERSION L34209.1 GI:508497
KEYWORDS prostaglandin synthase-2.
SOURCE Homo sapiens foreskin DNA.
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia;
Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1972)
AUTHORS Tazawa,R., Xu,X.M., Wu,K.K. and Wang,L.H.
TITLE Characterization of the genomic structure, chromosomal location and
promoter of human prostaglandin H synthase-2 gene
JOURNAL Biochem. Biophys. Res. Commun. 203, 190-199 (1994)
MEDLINE 94354801
FEATURES Location/Qualifiers
source 1..1972
/organism="Homo sapiens"
/db_xref="taxon:9606"
/cell_type="fibroblast"
/tissue_type="foreskin"
promoter 1..1835
/partial
/evidence=experimental
mRNA 1835..>1972
/gene="PGHS-2"
/product="prostaglandin synthase-2"
gene 1835..1972
/gene="PGHS-2"
TATA_signal 1861..1866
/gene="PGHS-2"
BASE COUNT 595 a 440 c 416 g 521 t
ORIGIN
1 aggattgtaa tgtaaaattt tagtactctc tcacagtatg gattctaaca tggcttctaa
61 cccaaactaa cattagtagc tctaactata aacttcaaat ttcagtagat gcaacctact
121 cctttaaaat gaaacagaag attgaaatta ttaaattatc aaaaagaaaa tgatccacgc
181 tcttagttga aatttcatgt aagattccat gcaataaata ggagtcccat aaatggaatg
241 atgaaatatg actagaggag gagaaaggct tcctagatga gatggaattt tagtcatccg
301 tgtctcatga agaatcagat gtgtacacta agcaaaacag ttaaaaaaaa aacctccaag
361 tgagtctctt atttattttt ttcttataag acttctacaa attgaggtac ctggtgtagt
421 tttatttcag gttttatgct gtcattttcc tgtaatgcta aggacttagg acataactga
481 attttctatt ttccacttct tttctggtgt gtgtgtatat atatatgtat atatacacac
541 acacatatac atatatatat tttttagtat ctcaccctca catgctggtg ggtgagcact
601 acccatgata gatgttaaac taaagcaaag atgaaattcc agctgtcaaa atctcccttc
661 catctaatta attcctcatc caactatgtt ccaaaacgag aatagaaaat tagccccaat
721 aagcccaggc aactgaaaag taaatgctat gttgtacttt gatccatggt cacaactcat
781 aatcttggaa aagtggacag aaaagacaaa agagtgaact ttaaaactcg aatttatttt
841 accagtatct cctatgaagg gctagtaacc aaaataatcc acgcatcagg gagagaaatg
901 ccttaaggca tacgttttgg acatttagcg tccctgcaaa ttctggccat cgccgcttcc
961 tttgtccatc agaaggcagg aaactttata ttggtgaccc gtggagctca cattaactat
1021 ttacagggta actgcttagg accagtatta tgaggagaat ttacctttcc cgcctctctt
1081 tccaagaaac aaggaggggg tgaaggtacg gagaacagta tttcttctgt tgaaagcaac
1141 ttagctacaa agataaatta cagctatgta cactgaaggt agctatttca ttccacaaaa
1201 taagagtttt ttaaaaagct atgtatgtat gtgctgcata tagagcagat atacagccta
1261 ttaagcgtcg tcactaaaac ataaaacatg tcagcctttc ttaaccttac tcgccccagt
1321 ctgtcccgac gtgacttcct cgaccctcta aagacgtaca gaccagacac ggcggcggcg
1381 gcgggagagg ggattccctg cgcccccgga cctcagggcc gctcagattc ctggagagga
1441 agccaagtgt ccttctgccc tcccccggta tcccatccaa ggcgatcagt ccacaactgg
1501 ctctcggaag cactcgggca aagactgcga agaagaaaag acatctggcg gaaacctgtg
1561 cgcctggggc ggtggaactc ggggaggaga gggagggatc agacaggaga gtggggacta
1621 ccccctctgc tcccaaattg gggcagcttc ctgggtttcc gattttctca tttccgtggg
1681 taaaaaaccc tgcccccacc ggcttacgca atttttttaa ggggagagga gggaaaaatt
1741 tgtggggggt acgaaaaggc ggaaagaaac agtcatttcg tcacatgggc ttggttttca
1801 gtcttataaa aaggaaggtt ctctcggtta gcgaccaatt gtcatacgac ttgcagtgag
1861 cgtcaggagc acgtccagga actcctcagc agcgcctcct tcagctccac agccagacgc
1921 cctcagacag caaagcctac ccccgcgccg cgccctgccc gccgctgcga tg