Potential for Improved Cancer Treatment with DNA Microarrays
Diffuse Large B-Cell Lymphoma (DLBCL)
- 25,000 new cases reported each year in the United States
- Fewer than half of DLBCL patients benefit from standard chemotherapy treatment.
69 tissue samples and 17,000 genes
![](chipfigs/DLBCL17k.jpg)
Recluster DLBCL samples using Germinal Center and Activated B-cell genes
![](chipfigs/DLBCLdendro.jpg)
Correlation of DNA microarray analysis and clinical outcomes of patients
![](chipfigs/DLBCLoutcomes.jpg)
(all figures with permission of Pat Brown)
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