Lessons About Stress from Yeast Microarrays
Verify Methodology - compare Northern blots to microarrays
![](chipfigs/northern.jpeg)
Expose yeast to 142 environmental perturbations: 900 Environmental Stress Response (ESR) genes alter expression
![](chipfigs/ESRgenes.jpg)
Regulation of ESR genes is dose dependent and transient
![](chipfigs/heatshockgenes.jpg)
Regulation of ESR genes inverted for opposite stress
![](chipfigs/ESRinverse.jpg)
(all figures with permission of Pat Brown)
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