Genomics, Proteomics, and Systems Biology
Reading Schedule: Spring 2018

Working Schedule

Dates Day Topics and Papers Read Before Class
Which Exam?
Jan 15 M
MLK Day
college closed
not yet
Jan 17 W Intro.; Freeman paper; read in class -->
exam 1
Jan 19 F genomes: one gene, one phenotype??
exam 1
Jan 22 M genomes: viruses alive, new domain??
exam 1
Jan 24 W genomes: n mutations per generation?
exam 1
Jan 26 F variations: human evolution
exam 1
first draft
M

Draft First Web Page

Choose an Area
Draft Mon Jan 29, class start time
Jan 29 M variations: human evolution complexity skin tone evolution
+ news story 1 + news story 2
exam 1
Jan 31 W variations: cancer heterogeneity
exam 1
Feb 2 F variations: variations across tissues rare variants
exam 1
Feb 5 M variations: random X inactivations X inactivations

exam 1
final version
M
First Web Page
Show What You Learned
Final Mon Feb 5, class start time
Feb 7
W
variations: copy number variations

CNV human neurons

exam 1
Feb 9 F variations: pharmacogenomics
exam 1
Feb 9 F 1st Exam TAKE HOME DUE Wed Feb 14, class start time
Feb 12 M no class
Dr. C. reviewing Biology Dept.
work on exam 1
Feb 14 W Ethics Discussion in Class

Turn In Exam

clinical trials OR incidental findings

DUE Wed Feb 14
class start time

Reading assigned during class

Feb 16 F variations: cancer mutations
exam 2
Feb 19 M metagenomics: microbiomes
exam 2
Feb 21 W metagenomics: obesity
exam 2
Feb 23 F metagenomics: artificial sweeteners
exam 2
Feb 26 M metagenomics: human habitats
exam 2
Feb 28
W
transcriptomics: cancer transcriptomes
exam 2
Mar 2 F transcriptomics: cancer transcriptomes
exam 2
Mar 5 M Spring Break ZZZZZZZ No Class
Mar 7 W Spring Break flip No Class
Mar 9 F Spring Break ZZZZZZZ No Class
Mar 12 M transcriptomics: RNAseq
exam 2
Mar 14 W transcriptomics: single cell RNAseq
exam 2
Mar 16 F epigenomics: parental input
exam 2
Mar 19 M epigenomics: ENCODE
exam 2
Mar 21 W epigenomics: epigenetic diseases
exam 2
Mar 23 F epigenomics: epigenetic breast cancer
exam 2
Mar 23 F 2nd Exam TAKE HOME DUE Wed March 28
class start time
Mar 26 M Future of the Field nanopore  OR  bioinformatics
OR GWAS to editing
final exam
Mar 28 W
Ethics Discussion in Class
Turn In Exam

epigenetic heretic OR ENCODE skeptic
OR microbiome skeptic
DUE Wed March 28
class start time


Readings assigned during class

Mar 30

F

epigenomics: chromatin shapes cancers

cell-of-origin chromatin

final exam

Review Paper
choose one
paper A or paper B or paper C
Summarize Paper & Every Figure Web page Due Friday
April 27, 2 pm
Apr 2 M Easter Break rest and relax

Apr 4 W proteomics: proteins vs mRNA

worm/fly proteomes
ICAT Method

final exam
Apr 6 F proteomics: interactome interactome defines disease
final exam
Apr 9 M proteomics: cancer
final exam
Apr 11 W proteomics: single cells
final exam
Apr 13
F
metabolomics: biomarkers for diagnosis pancreatic cancer vs. pancreatitis
final exam
April 16 M
no class meeting
work on your paper summaries

Apr 18 W metabolomics: naked mole rat

anticancer properties
naked mole rat
hyaluronan

final exam
Apr 20 F metabolomics: drug-biota interactions
final exam
Apr 23 M systems biology: interacting gene networks I
higher order networks
final exam
Apr 25 W

systems biology: interacting gene networks II

global genetic interactions
final exam
Apr 27 F systems biology: genetics and networks

conservation of systems
final exam
Apr 27 F

submit review
paper A or paper B or paper C

Summarize Paper & Every Figure Web page Due Friday
April 27, 2 pm
Apr 30 M systems biology: mammalian circuits
trans-activating circuits
final exam
May 2 W systems biology: interactome disease-disease comparisons
final exam
May 4 F systems biology: lung adenocarcinoma TF and lncRNA networks
final exam
May 7 M

Last class & final exam emailed

Course Evaluations
Fellowships

Course Evaluations!

May 9 W No Classes campus-wide Celebration of Research
Give a Talk/ Hear Your Friends
May 9- 15 M - M Final Exam
Due May 14, 9 am
 submit electronic copy by email the rest of your life!

Genomics Overview

Genomics Syllabus

Biology Home Page


© Copyright 2018 Department of Biology, Davidson College, Davidson, NC 28035
Send comments, questions, and suggestions to:
macampbell@davidson.edu