Home Page

Pathogen Description

Pathogen Life Cycle

Innate Immune Response

Humoral Immune Response

Cellular Immune Response

Evasion of Immune System Detection

Future Directions

(2005). "Rocky Mountain Spotted Fever." CDC: Center for Disease Control and Prevention. Retrieved 26 January, 2007, from http://www.cdc.gov/ncidod/dvrd/rmsf/index.htm.

Azad, A.F., C.B. Beard. (1998). Rickettsial pathogens and their arthropod vectors. Emerging Infectious Diseases: 4, 1-9. Retrieved 1 January, 2007, from http://www.cdc.gov/ncidod/eid/vol4no2/azad.htm.

Clifton, D.R., E. Rydkina, H. Huyck, et al. (2005) Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB. International Journal of Medical Microbiology, 295: 267-278.

Clifton, D.R., R.A. Goss, S.K. Sahni, et al. (1998). NF-kB-dependent inhibition of apoptosis is essential for host cell survival during Rickettsia rickettsii infection. Proceedings of the National Academy of Sciences of the United States of America, 95: 4646-4651.

Gage, K., T.R. Jerrells. (1992). Demonstration and partial characterization of antigens of Rickettsia rhipicephali that induce cross-reactive cellular and humoral immune responses to Rickettsia rickettsii. Infection and Immunity: 60, 5099-5106.

Heinzen, R.A., S.S. Grieshaber, L.S. van Kirk, C.J. Devin. (1999) Dynamics of actin-based movement by Rickettsia rickettsii in vero cells. Infection and Immunity, 67: 4201-4207.

Janeway, C.A., et al. (2005). Immunobiology: The Immune System in Health and Disease. New York: Garland Science Publishing, 753-757.

Rudakov, N.V., Shpynov, S.N., Samoilenko, I.E., Tankibaev, M.A. (2003) Ecology and Epidemiology of spotted fever group Rickettsiae and new data from their study in Russia and Kazakhstan. K.E. Hechemy, et al. New York, New York Academy of Sciences, 990: 12-24.

Rydkina, E., D.J. Silverman, S.K. Sahni. (2005). Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response. Cellular Microbiology, 7: 1519-1530.

Silverman, D.J., L.A. Santucci, N. Meyers, Z. Sekeyova. (1992) Penetration of host cells by Rickettsia rickettsii appears to be mediated by a phospholipase of rickettsial origin. Infection and Immunity: 60, 2733-2740.

Teysseire, N., J.A. Boudier, D. Raoult. (1994). Rickettsia conorii entry into vero cells. Infection and Immunity, 63: 366-374.

Turko, J., H.H. Winkler. (1990) Selection of alpha/beta interferon- and gamma interferon-resistant rickettsiae by passage of Rickettsia prowazekii in L929 cells. Infection and Immunity, 58: 3279-3285.

Walker, D.H., F.W. Henderson. (1977) Effect of immunosuppression on Rickettsia rickettsii infection in guinea pigs. Infection and immunity, 20: 221-227.

Walker, D.H., Valbuena, G.A., Olano, J.P. (2003). Pathogenic mechanisms of diseases caused by Rickettsia. Rickettsiology: Present and Future Directions. K.E. Hechemy, et al. New York, New York Academy of Sciences, 990: 1-11.

Walker, D.H. (2006) Targeting Rickettsia. New England Journal of Medicine, 354: 1418-1420.

Wattam, R. (2004). "Rickettsia rickettsii." Retrieved 1 January, 2007, from http://pathport.vbi.vt.edu/pathinfo/pathogens/rickettsii.html.

Williams, J.C., D. H. Walker, M.G. Peacock, S.T. Stewart. (1986). Humoral immune response to Rocky Mountain Spotted Fever in experimentally infected guinea pigs: Immunoprecipitation of lactoperoxidase 125I-labeled proteins and detection of soluble antigens of Rickettsia rickettsii. Infection and Immunity: 52, 120-127.

Winslow, G.M., Yager, E., Shu-Yi Li, J. (2003). Mechanisms of humoral immunity during Ehrlichia chaffeensis infection. Rickettsiology: Present and Future Directions. K.E. Hechemy, et al. New York, New York Academy of Sciences, 990: 435-443.

Back to top

Davidson College Homepage