GENOMICS, PROTEOMICS & SYSTEMS BIOLOGY
INVESTIGATIONS OF HUMAN DISEASES

Davidson College BIO309 Fall 2007

 

Genomics and Systems Biology is a cutting-edge interdisciplinary field that presents unprecedented opportunities for exploring biology from a unique perspective. This perspective combines reductionist genetics with wholistic systems approaches. Armed with powerful bioinformatics tools, the investigator can build whole system models to discover emergent properties that lie beyond the reach of classical nonintegrative research.

During the Fall 2007 course in Genomics, Proteomics and Systems Biology at Davidson College, led by Dr. Karmella A. Haynes, six Davidson College students used an array of powerful bioinformatics tools to investigate genes that are linked to human diseases. They set out to ellucidate the molecular mechanisms underlying the diseases by constructing models that integrate original and published genomics, transcriptomics, and proteomics data.

This web site was produced as an assignment for an undergraduate course at Davidson College. Send inquiries to kahaynes at davidson (.edu).

 

Cecie Blair
XPA and the skin disease xeroderma pigmentosum

Kelli Carroll
MSH6, DNA repair, and colorectal cancer

Dominic Ippolito
Using systems biology to understand paraganglioma

Shannon Pittman
SURF1 and Leigh Syndrome

Anders Wells
Genomics of human lupus antigen

Erin Zwack
TSG101 mutations' link to cancer