Immunology - BIO307

Hyperlinked Human Histology,

Molecular Movies

Course Materials for Spring 2006

Immunology Syllabus for Spring 2006

Immunology Reading Schedule for Spring 2006

Immunology Important Dates for Spring 2006


Immunology Student Web Pages

Immunology Standards for Web Pages

Immunology Web Resources (including old tests)

Chemokine Mini-lectures Online (courtesy of University of Stony Brook)

Molecular Movies - Flash Animations to help students learn immunology.

These movies require the Flash plug-in which is a free option from Macromedia, and comes with browser (Netscape or IE) versions 4.5 or later. If you click on one of the animations, it will search your computer to find the correct plug-in. If you do not have it, it will provide you with a button for downloading the correct plug-in, free of charge, or you may click here .
This work was funded in part by a Mellon Technology Fellowship from the Associated Colleges of the South, and Davidson College's Faculty Summmer Support program.

Awards for Molecular Movies

Selected as "Hot Site", Netwatch, 12 November, 1999.

Selected as HMS Beagle's "Web Pick of the Day" 30 November, 1999.

5 Star Rating MERLOT web site, September, 2002.

Harvey Project to advance the teaching of physiology. December, 2005.

Somatic Recombination of a light chain to demonstrate how antibodies can bind to so many different epitopes.

MHC I antigen loading - shows how MHC class one molecules acquire their antigens for presentation on the cell surface.

MHC II antigen loading - shows how MHC class two molecules acquire their antigens for presentation on the cell surface.

IP3 and Ca2+ ions as second messengers - shows how ligand binding to a receptor initiates the production of IP3 and release of Ca2+ ions from the ER.

B Cell Maturation - shows intracellular and extracellular interactions that illustrate the maturation stages of B cells in the bone marrow.

Activation of B Cells with Thymus-Independent (TI) Antigen - shows the role of the B cell receptor and coreceptor when challenged with a bacterial or viral anitgen that has many copies of a single epitope.

B Cell Selection - shows how B cells that bind to self-antigen are removed from the repertoire of B cells with randomly generated binding specificities. Also shows that non-reactive B cells are permitted to enter general circulation.

T Cell Selection - this series of animations shows T Cell development, Positive Selection, and Negative Selection. The viewer can choose which process he or she wants to see. The animations were created by and generously donated to Davidson College by Dr. Victor Lemas of BioCreations.

MAPK - an animation which shows how cell surface receptors lead to gene activation. This pathway is called the MAP Kinase pathway. The animation was created by and generously donated to Davidson College by Dr. Victor Lemas of BioCreations.

RT-PCR - shows how the method of reverse transcriptase-PCR is performed and some sample data are produced.

If you cannot see the animation listed above after you have clicked on their links, click on the "Get Shockwave" button and download the FREE Shockwave Flash Plugin.

Hyperlinked Human Histology

This is the Hyperlinked Human Histology (HHH) Home Page. This is being developed for students to use when they want to tie together the micro and the macro of immunology. For example, in immunology classes, students learn about the proteins involved in T cell responses, but lose sight of where this happens in the body.

Click here
to enter HHH. Soon there will be a human image that will allow the user to pass the mouse over an organ and click on that organ to zoom in for histological perspectives. The user will see images with blue boxes which are hot spots that are hyperlinked to higher magnifications. To go back to lower powers, just click on the image outside of the blue boxes to zoom out.

In case you cannot see the Flash image, you can click on the five links below to skip the Flash image.

List of organs

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