genbank.html

Pyruvate Carboxylase in Five Organisms

Click here to see cDNA and protein sequence for Apergillus terreus

Click here to see the cDNA and protein sequence for Rattus norvegicus

Click here to see the whole gene and protein sequence for Saccharomyces cerevisiae

Click here to see cDNA and protein sequence for Homo Sapiens

Click here to see the whole gene and protein sequence for Lactococtis lactis

         O   O                                                       O                                O
          | | | |              pyruvate                             | |            H₂O             | |
   ^-O--C--C--CH₃^{--------------}^{> O==C==O
+ -:C--CH}₃^{-----------> H}₃^C--C+^NADH+^H+
^{(Pyruvate)
carboxylase
NAD+
|}
^O-

^{This reaction allows the electron
transport chain to function in the mitochondria. The mechanism converts
glucose derivatives (pyruvate) into energy in the bonds of ATP.}

^{Click here to see the rasmol image of
pyruvate carboxylase complexed with pyruvamide: Rasmol}

^{Click here to see the largest the largest open reading
frame in pyruvate carboxylase: ORF}

^{Click here to see the molecular weight of pyruvate
carboxylase: Molecular Weight}

^{Click here to see the hydropathy plot for pyruvate
carboxylase: Kyte
Doolittle}

^{Click here to see the most hydrophilic region of
this protein: Antigenicity}

^{Click here to see the secondary structure of pyruvate
carboxylase: Secondary
Structure}

^{Click here to see multiple sequence alignments of
this protein in these five organisms: Seq.
alignment}

Click here to see the percentage of conservation of amino acids in pyruvate carboxlase
between these five organisms: Conservation

^{Davidson
Molecular Home Page}

^{Sean Burke Home Page}